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Generation and characterization of human induced pluripotent stem cell lines from a familial Alzheimer's disease PSEN1 A246E patient and a non-demented family member bearing wild-type PSEN1.
Muñoz SS, Balez R, Castro Cabral-da-Silva ME, Berg T, Engel M, Bax M, Do-Ha D, Stevens CH, Greenough M, Bush A, Ooi L. Muñoz SS, et al. Among authors: bush a. Stem Cell Res. 2018 Aug;31:227-230. doi: 10.1016/j.scr.2018.08.006. Epub 2018 Aug 13. Stem Cell Res. 2018. PMID: 30138848 Free article.
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI. Duce JA, et al. Among authors: bush ai. Cell. 2010 Sep 17;142(6):857-67. doi: 10.1016/j.cell.2010.08.014. Cell. 2010. PMID: 20817278 Free PMC article.
Syntaxin 5 is required for copper homeostasis in Drosophila and mammals.
Norgate M, Southon A, Greenough M, Cater M, Farlow A, Batterham P, Bush AI, Subramaniam VN, Burke R, Camakaris J. Norgate M, et al. Among authors: bush ai. PLoS One. 2010 Dec 20;5(12):e14303. doi: 10.1371/journal.pone.0014303. PLoS One. 2010. PMID: 21188142 Free PMC article.
The Alzheimer's therapeutic PBT2 promotes amyloid-β degradation and GSK3 phosphorylation via a metal chaperone activity.
Crouch PJ, Savva MS, Hung LW, Donnelly PS, Mot AI, Parker SJ, Greenough MA, Volitakis I, Adlard PA, Cherny RA, Masters CL, Bush AI, Barnham KJ, White AR. Crouch PJ, et al. Among authors: bush ai. J Neurochem. 2011 Oct;119(1):220-30. doi: 10.1111/j.1471-4159.2011.07402.x. Epub 2011 Aug 25. J Neurochem. 2011. PMID: 21797865 Free article.
Presenilin promotes dietary copper uptake.
Southon A, Greenough MA, Ganio G, Bush AI, Burke R, Camakaris J. Southon A, et al. Among authors: bush ai. PLoS One. 2013 May 7;8(5):e62811. doi: 10.1371/journal.pone.0062811. Print 2013. PLoS One. 2013. PMID: 23667524 Free PMC article.
Copper: from neurotransmission to neuroproteostasis.
Opazo CM, Greenough MA, Bush AI. Opazo CM, et al. Among authors: bush ai. Front Aging Neurosci. 2014 Jul 3;6:143. doi: 10.3389/fnagi.2014.00143. eCollection 2014. Front Aging Neurosci. 2014. PMID: 25071552 Free PMC article. Review.
1,985 results