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Neolymphostin A Is a Covalent Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitor That Employs an Unusual Electrophilic Vinylogous Ester.
Castro-Falcón G, Seiler GS, Demir Ö, Rathinaswamy MK, Hamelin D, Hoffmann RM, Makowski SL, Letzel AC, Field SJ, Burke JE, Amaro RE, Hughes CC. Castro-Falcón G, et al. J Med Chem. 2018 Dec 13;61(23):10463-10472. doi: 10.1021/acs.jmedchem.8b00975. Epub 2018 Nov 28. J Med Chem. 2018. PMID: 30380865 Free PMC article.
Nature's Combinatorial Biosynthesis Produces Vatiamides A-F.
Moss NA, Seiler G, Leão TF, Castro-Falcón G, Gerwick L, Hughes CC, Gerwick WH. Moss NA, et al. Among authors: castro falcon g. Angew Chem Int Ed Engl. 2019 Jul 1;58(27):9027-9031. doi: 10.1002/anie.201902571. Epub 2019 May 28. Angew Chem Int Ed Engl. 2019. PMID: 31071229 Free PMC article.
Biosynthesis and antifungal activity of fungus-induced O-methylated flavonoids in maize.
Förster C, Handrick V, Ding Y, Nakamura Y, Paetz C, Schneider B, Castro-Falcón G, Hughes CC, Luck K, Poosapati S, Kunert G, Huffaker A, Gershenzon J, Schmelz EA, Köllner TG. Förster C, et al. Among authors: castro falcon g. Plant Physiol. 2022 Jan 20;188(1):167-190. doi: 10.1093/plphys/kiab496. Plant Physiol. 2022. PMID: 34718797 Free PMC article.
Multiple genes recruited from hormone pathways partition maize diterpenoid defences.
Ding Y, Murphy KM, Poretsky E, Mafu S, Yang B, Char SN, Christensen SA, Saldivar E, Wu M, Wang Q, Ji L, Schmitz RJ, Kremling KA, Buckler ES, Shen Z, Briggs SP, Bohlmann J, Sher A, Castro-Falcon G, Hughes CC, Huffaker A, Zerbe P, Schmelz EA. Ding Y, et al. Among authors: castro falcon g. Nat Plants. 2019 Oct;5(10):1043-1056. doi: 10.1038/s41477-019-0509-6. Epub 2019 Sep 16. Nat Plants. 2019. PMID: 31527844
Mass Spectrometry-Based Visualization of Molecules Associated with Human Habitats.
Petras D, Nothias LF, Quinn RA, Alexandrov T, Bandeira N, Bouslimani A, Castro-Falcón G, Chen L, Dang T, Floros DJ, Hook V, Garg N, Hoffner N, Jiang Y, Kapono CA, Koester I, Knight R, Leber CA, Ling TJ, Luzzatto-Knaan T, McCall LI, McGrath AP, Meehan MJ, Merritt JK, Mills RH, Morton J, Podvin S, Protsyuk I, Purdy T, Satterfield K, Searles S, Shah S, Shires S, Steffen D, White M, Todoric J, Tuttle R, Wojnicz A, Sapp V, Vargas F, Yang J, Zhang C, Dorrestein PC. Petras D, et al. Anal Chem. 2016 Nov 15;88(22):10775-10784. doi: 10.1021/acs.analchem.6b03456. Epub 2016 Oct 24. Anal Chem. 2016. PMID: 27732780 Free PMC article.
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