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Smoothened stimulation by membrane sterols drives Hedgehog pathway activity.
Deshpande I, Liang J, Hedeen D, Roberts KJ, Zhang Y, Ha B, Latorraca NR, Faust B, Dror RO, Beachy PA, Myers BR, Manglik A. Deshpande I, et al. Among authors: zhang y. Nature. 2019 Jul;571(7764):284-288. doi: 10.1038/s41586-019-1355-4. Epub 2019 Jul 1. Nature. 2019. PMID: 31263273 Free PMC article.
Dispatched uses Na+ flux to power release of lipid-modified Hedgehog.
Wang Q, Asarnow DE, Ding K, Mann RK, Hatakeyama J, Zhang Y, Ma Y, Cheng Y, Beachy PA. Wang Q, et al. Among authors: zhang y. Nature. 2021 Nov;599(7884):320-324. doi: 10.1038/s41586-021-03996-0. Epub 2021 Oct 27. Nature. 2021. PMID: 34707294 Free PMC article.
Massively parallel in vivo Perturb-seq reveals cell-type-specific transcriptional networks in cortical development.
Zheng X, Wu B, Liu Y, Simmons SK, Kim K, Clarke GS, Ashiq A, Park J, Li J, Wang Z, Tong L, Wang Q, Rajamani KT, Muñoz-Castañeda R, Mu S, Qi T, Zhang Y, Ngiam ZC, Ohte N, Hanashima C, Wu Z, Xu X, Levin JZ, Jin X. Zheng X, et al. Among authors: zhang y. Cell. 2024 May 14:S0092-8674(24)00476-8. doi: 10.1016/j.cell.2024.04.050. Online ahead of print. Cell. 2024. PMID: 38772369 Free article.
A role of PIEZO1 in iron metabolism in mice and humans.
Ma S, Dubin AE, Zhang Y, Mousavi SAR, Wang Y, Coombs AM, Loud M, Andolfo I, Patapoutian A. Ma S, et al. Among authors: zhang y. Cell. 2021 Feb 18;184(4):969-982.e13. doi: 10.1016/j.cell.2021.01.024. Epub 2021 Feb 10. Cell. 2021. PMID: 33571427 Free PMC article.
The role of somatosensory innervation of adipose tissues.
Wang Y, Leung VH, Zhang Y, Nudell VS, Loud M, Servin-Vences MR, Yang D, Wang K, Moya-Garzon MD, Li VL, Long JZ, Patapoutian A, Ye L. Wang Y, et al. Among authors: zhang y. Nature. 2022 Sep;609(7927):569-574. doi: 10.1038/s41586-022-05137-7. Epub 2022 Aug 31. Nature. 2022. PMID: 36045288 Free PMC article.
Molecular mechanism of GPCR spatial organization at the plasma membrane.
Kockelkoren G, Lauritsen L, Shuttle CG, Kazepidou E, Vonkova I, Zhang Y, Breuer A, Kennard C, Brunetti RM, D'Este E, Weiner OD, Uline M, Stamou D. Kockelkoren G, et al. Among authors: zhang y. Nat Chem Biol. 2024 Feb;20(2):142-150. doi: 10.1038/s41589-023-01385-4. Epub 2023 Jul 17. Nat Chem Biol. 2024. PMID: 37460675
240,735 results
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