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Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition.
Morillas M, Gómez-Puertas P, Bentebibel A, Sellés E, Casals N, Valencia A, Hegardt FG, Asins G, Serra D. Morillas M, et al. Among authors: casals n. J Biol Chem. 2003 Mar 14;278(11):9058-63. doi: 10.1074/jbc.M209999200. Epub 2002 Dec 23. J Biol Chem. 2003. PMID: 12499375 Free article.
Central ceramide-induced hypothalamic lipotoxicity and ER stress regulate energy balance.
Contreras C, González-García I, Martínez-Sánchez N, Seoane-Collazo P, Jacas J, Morgan DA, Serra D, Gallego R, Gonzalez F, Casals N, Nogueiras R, Rahmouni K, Diéguez C, López M. Contreras C, et al. Among authors: casals n. Cell Rep. 2014 Oct 9;9(1):366-377. doi: 10.1016/j.celrep.2014.08.057. Epub 2014 Oct 2. Cell Rep. 2014. PMID: 25284795 Free PMC article.
Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.
Malandrino MI, Fucho R, Weber M, Calderon-Dominguez M, Mir JF, Valcarcel L, Escoté X, Gómez-Serrano M, Peral B, Salvadó L, Fernández-Veledo S, Casals N, Vázquez-Carrera M, Villarroya F, Vendrell JJ, Serra D, Herrero L. Malandrino MI, et al. Among authors: casals n. Am J Physiol Endocrinol Metab. 2015 May 1;308(9):E756-69. doi: 10.1152/ajpendo.00362.2014. Epub 2015 Feb 24. Am J Physiol Endocrinol Metab. 2015. PMID: 25714670 Free article.
Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia.
Rinaldi C, Schmidt T, Situ AJ, Johnson JO, Lee PR, Chen KL, Bott LC, Fadó R, Harmison GH, Parodi S, Grunseich C, Renvoisé B, Biesecker LG, De Michele G, Santorelli FM, Filla A, Stevanin G, Dürr A, Brice A, Casals N, Traynor BJ, Blackstone C, Ulmer TS, Fischbeck KH. Rinaldi C, et al. Among authors: casals n. JAMA Neurol. 2015 May;72(5):561-70. doi: 10.1001/jamaneurol.2014.4769. JAMA Neurol. 2015. PMID: 25751282 Free PMC article.
Novel Regulation of the Synthesis of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus.
Fadó R, Soto D, Miñano-Molina AJ, Pozo M, Carrasco P, Yefimenko N, Rodríguez-Álvarez J, Casals N. Fadó R, et al. Among authors: casals n. J Biol Chem. 2015 Oct 16;290(42):25548-60. doi: 10.1074/jbc.M115.681064. Epub 2015 Sep 3. J Biol Chem. 2015. PMID: 26338711 Free PMC article.
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