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Tuning Subunit Vaccines with Novel TLR Triagonist Adjuvants to Generate Protective Immune Responses against Coxiella burnetii.
Gilkes AP, Albin TJ, Manna S, Supnet M, Ruiz S, Tom J, Badten AJ, Jain A, Nakajima R, Felgner J, Davies DH, Stetkevich SA, Zlotnik A, Pearlman E, Nalca A, Felgner PL, Esser-Kahn AP, Burkhardt AM. Gilkes AP, et al. J Immunol. 2020 Feb 1;204(3):611-621. doi: 10.4049/jimmunol.1900991. Epub 2019 Dec 23. J Immunol. 2020. PMID: 31871024
Covalently coupled immunostimulant heterodimers.
Mancini RJ, Tom JK, Esser-Kahn AP. Mancini RJ, et al. Among authors: tom jk. Angew Chem Int Ed Engl. 2014 Jan 3;53(1):189-92. doi: 10.1002/anie.201306551. Epub 2013 Nov 20. Angew Chem Int Ed Engl. 2014. PMID: 24259411 Free PMC article.
Directing the immune system with chemical compounds.
Mancini RJ, Stutts L, Ryu KA, Tom JK, Esser-Kahn AP. Mancini RJ, et al. Among authors: tom jk. ACS Chem Biol. 2014 May 16;9(5):1075-85. doi: 10.1021/cb500079s. Epub 2014 Apr 30. ACS Chem Biol. 2014. PMID: 24690004 Free PMC article. Review.
In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity.
Lynn GM, Laga R, Darrah PA, Ishizuka AS, Balaci AJ, Dulcey AE, Pechar M, Pola R, Gerner MY, Yamamoto A, Buechler CR, Quinn KM, Smelkinson MG, Vanek O, Cawood R, Hills T, Vasalatiy O, Kastenmüller K, Francica JR, Stutts L, Tom JK, Ryu KA, Esser-Kahn AP, Etrych T, Fisher KD, Seymour LW, Seder RA. Lynn GM, et al. Among authors: tom jk. Nat Biotechnol. 2015 Nov;33(11):1201-10. doi: 10.1038/nbt.3371. Epub 2015 Oct 26. Nat Biotechnol. 2015. PMID: 26501954 Free PMC article.
Linked Toll-Like Receptor Triagonists Stimulate Distinct, Combination-Dependent Innate Immune Responses.
Albin TJ, Tom JK, Manna S, Gilkes AP, Stetkevich SA, Katz BB, Supnet M, Felgner J, Jain A, Nakajima R, Jasinskas A, Zlotnik A, Pearlman E, Davies DH, Felgner PL, Burkhardt AM, Esser-Kahn AP. Albin TJ, et al. Among authors: tom jk. ACS Cent Sci. 2019 Jul 24;5(7):1137-1145. doi: 10.1021/acscentsci.8b00823. Epub 2019 Jun 27. ACS Cent Sci. 2019. PMID: 31403067 Free PMC article.
20 results