Williams GT - Search Results

1

Lect2 deficiency is characterised by altered cytokine levels and promotion of intestinal tumourigenesis.

Greenow KR, Zverev M, May S, Kendrick H, Williams GT, Phesse T, Parry L. Greenow KR, et al. Among authors: williams gt. Oncotarget. 2018 Nov 23;9(92):36430-36443. doi: 10.18632/oncotarget.26335. eCollection 2018 Nov 23. Oncotarget. 2018. PMID: 30559928 Free PMC article.

2

Cited1 deficiency suppresses intestinal tumorigenesis.

Méniel V, Song F, Phesse T, Young M, Poetz O, Parry L, Jenkins JR, Williams GT, Dunwoodie SL, Watson A, Clarke AR. Méniel V, et al. Among authors: williams gt. PLoS Genet. 2013;9(8):e1003638. doi: 10.1371/journal.pgen.1003638. Epub 2013 Aug 1. PLoS Genet. 2013. PMID: 23935526 Free PMC article.

3

Wnt-driven intestinal tumourigenesis is suppressed by Chk1 deficiency but enhanced by conditional haploinsufficiency.

Greenow KR, Clarke AR, Williams GT, Jones R. Greenow KR, et al. Among authors: williams gt. Oncogene. 2014 Jul 31;33(31):4089-96. doi: 10.1038/onc.2013.371. Epub 2013 Sep 16. Oncogene. 2014. PMID: 24037525

4

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer.

Jezkova J, Williams JS, Pinto F, Sammut SJ, Williams GT, Gollins S, McFarlane RJ, Reis RM, Wakeman JA. Jezkova J, et al. Among authors: williams gt, williams js. Oncotarget. 2016 Mar 8;7(10):11478-86. doi: 10.18632/oncotarget.7202. Oncotarget. 2016. PMID: 26862851 Free PMC article.

5

Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation.

May S, Owen H, Phesse TJ, Greenow KR, Jones GR, Blackwood A, Cook PC, Towers C, Gallimore AM, Williams GT, Stürzl M, Britzen-Laurent N, Sansom OJ, MacDonald AS, Bird AP, Clarke AR, Parry L. May S, et al. Among authors: williams gt. J Pathol. 2018 Jul;245(3):270-282. doi: 10.1002/path.5074. Epub 2018 May 16. J Pathol. 2018. PMID: 29603746 Free PMC article.

6

Epithelial Pten is dispensable for intestinal homeostasis but suppresses adenoma development and progression after Apc mutation.

Marsh V, Winton DJ, Williams GT, Dubois N, Trumpp A, Sansom OJ, Clarke AR. Marsh V, et al. Among authors: williams gt. Nat Genet. 2008 Dec;40(12):1436-44. doi: 10.1038/ng.256. Epub 2008 Nov 16. Nat Genet. 2008. PMID: 19011632

7

Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine.

Holik AZ, Young M, Krzystyniak J, Williams GT, Metzger D, Shorning BY, Clarke AR. Holik AZ, et al. Among authors: williams gt. PLoS Genet. 2014 Jul 10;10(7):e1004453. doi: 10.1371/journal.pgen.1004453. eCollection 2014 Jul. PLoS Genet. 2014. PMID: 25010414 Free PMC article.

8

PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine.

Davies EJ, Marsh Durban V, Meniel V, Williams GT, Clarke AR. Davies EJ, et al. Among authors: williams gt. J Pathol. 2014 May;233(1):27-38. doi: 10.1002/path.4312. Epub 2014 Jan 23. J Pathol. 2014. PMID: 24293351

9

Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium.

Daly CS, Shaw P, Ordonez LD, Williams GT, Quist J, Grigoriadis A, Van Es JH, Clevers H, Clarke AR, Reed KR. Daly CS, et al. Among authors: williams gt. Oncogene. 2017 Mar 30;36(13):1793-1803. doi: 10.1038/onc.2016.342. Epub 2016 Oct 3. Oncogene. 2017. PMID: 27694902 Free PMC article.

10

PTEN loss and KRAS activation cooperate in murine biliary tract malignancies.

Marsh V, Davies EJ, Williams GT, Clarke AR. Marsh V, et al. Among authors: williams gt. J Pathol. 2013 Jun;230(2):165-73. doi: 10.1002/path.4189. J Pathol. 2013. PMID: 23483557

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