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An efficient rapid system for profiling the cellular activities of molecular libraries.
Melnick JS, Janes J, Kim S, Chang JY, Sipes DG, Gunderson D, Jarnes L, Matzen JT, Garcia ME, Hood TL, Beigi R, Xia G, Harig RA, Asatryan H, Yan SF, Zhou Y, Gu XJ, Saadat A, Zhou V, King FJ, Shaw CM, Su AI, Downs R, Gray NS, Schultz PG, Warmuth M, Caldwell JS. Melnick JS, et al. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3153-8. doi: 10.1073/pnas.0511292103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492761 Free PMC article.
Dark chemical matter as a promising starting point for drug lead discovery.
Wassermann AM, Lounkine E, Hoepfner D, Le Goff G, King FJ, Studer C, Peltier JM, Grippo ML, Prindle V, Tao J, Schuffenhauer A, Wallace IM, Chen S, Krastel P, Cobos-Correa A, Parker CN, Davies JW, Glick M. Wassermann AM, et al. Nat Chem Biol. 2015 Dec;11(12):958-66. doi: 10.1038/nchembio.1936. Epub 2015 Oct 19. Nat Chem Biol. 2015. PMID: 26479441
Genome-scale functional profiling of the mammalian AP-1 signaling pathway.
Chanda SK, White S, Orth AP, Reisdorph R, Miraglia L, Thomas RS, DeJesus P, Mason DE, Huang Q, Vega R, Yu DH, Nelson CG, Smith BM, Terry R, Linford AS, Yu Y, Chirn GW, Song C, Labow MA, Cohen D, King FJ, Peters EC, Schultz PG, Vogt PK, Hogenesch JB, Caldwell JS. Chanda SK, et al. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12153-8. doi: 10.1073/pnas.1934839100. Epub 2003 Sep 26. Proc Natl Acad Sci U S A. 2003. PMID: 14514886 Free PMC article.
Chemical-text hybrid search engines.
Zhou Y, Zhou B, Jiang S, King FJ. Zhou Y, et al. J Chem Inf Model. 2010 Jan;50(1):47-54. doi: 10.1021/ci900380s. J Chem Inf Model. 2010. PMID: 20047295
457 results