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Mechanistic Target of Rapamycin (mTOR) Inhibition Synergizes with Reduced Internal Ribosome Entry Site (IRES)-mediated Translation of Cyclin D1 and c-MYC mRNAs to Treat Glioblastoma.
Holmes B, Lee J, Landon KA, Benavides-Serrato A, Bashir T, Jung ME, Lichtenstein A, Gera J. Holmes B, et al. Among authors: bashir t. J Biol Chem. 2016 Jul 1;291(27):14146-14159. doi: 10.1074/jbc.M116.726927. Epub 2016 May 11. J Biol Chem. 2016. PMID: 27226604 Free PMC article.
Protor-2 interacts with tristetraprolin to regulate mRNA stability during stress.
Holmes B, Artinian N, Anderson L, Martin J, Masri J, Cloninger C, Bernath A, Bashir T, Benavides-Serrato A, Gera J. Holmes B, et al. Among authors: bashir t. Cell Signal. 2012 Jan;24(1):309-15. doi: 10.1016/j.cellsig.2011.09.015. Epub 2011 Sep 22. Cell Signal. 2012. PMID: 21964062 Free PMC article.
Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity.
Martin J, Masri J, Cloninger C, Holmes B, Artinian N, Funk A, Ruegg T, Anderson L, Bashir T, Bernath A, Lichtenstein A, Gera J. Martin J, et al. Among authors: bashir t. J Biol Chem. 2011 May 6;286(18):16402-13. doi: 10.1074/jbc.M110.205096. Epub 2011 Mar 16. J Biol Chem. 2011. PMID: 21454539 Free PMC article.
136 results