Jeffrey PD - Search Results

1

An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor.

Paczkowski JE, McCready AR, Cong JP, Li Z, Jeffrey PD, Smith CD, Henke BR, Hughson FM, Bassler BL. Paczkowski JE, et al. Among authors: jeffrey pd. ACS Chem Biol. 2019 Mar 15;14(3):378-389. doi: 10.1021/acschembio.8b00971. Epub 2019 Mar 4. ACS Chem Biol. 2019. PMID: 30763066 Free PMC article.

2

The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.

Kelly RC, Bolitho ME, Higgins DA, Lu W, Ng WL, Jeffrey PD, Rabinowitz JD, Semmelhack MF, Hughson FM, Bassler BL. Kelly RC, et al. Among authors: jeffrey pd. Nat Chem Biol. 2009 Dec;5(12):891-5. doi: 10.1038/nchembio.237. Epub 2009 Oct 18. Nat Chem Biol. 2009. PMID: 19838203 Free PMC article.

3

A strategy for antagonizing quorum sensing.

Chen G, Swem LR, Swem DL, Stauff DL, O'Loughlin CT, Jeffrey PD, Bassler BL, Hughson FM. Chen G, et al. Among authors: jeffrey pd. Mol Cell. 2011 Apr 22;42(2):199-209. doi: 10.1016/j.molcel.2011.04.003. Mol Cell. 2011. PMID: 21504831 Free PMC article.

4

Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.

Boyaci H, Shah T, Hurley A, Kokona B, Li Z, Ventocilla C, Jeffrey PD, Semmelhack MF, Fairman R, Bassler BL, Hughson FM. Boyaci H, et al. Among authors: jeffrey pd. PLoS Biol. 2016 May 24;14(5):e1002464. doi: 10.1371/journal.pbio.1002464. eCollection 2016 May. PLoS Biol. 2016. PMID: 27219477 Free PMC article.

5

Inhibitor Mimetic Mutations in the Pseudomonas aeruginosa PqsE Enzyme Reveal a Protein-Protein Interaction with the Quorum-Sensing Receptor RhlR That Is Vital for Virulence Factor Production.

Taylor IR, Paczkowski JE, Jeffrey PD, Henke BR, Smith CD, Bassler BL. Taylor IR, et al. Among authors: jeffrey pd. ACS Chem Biol. 2021 Apr 16;16(4):740-752. doi: 10.1021/acschembio.1c00049. Epub 2021 Apr 1. ACS Chem Biol. 2021. PMID: 33793200 Free PMC article.

6

Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing.

Neiditch MB, Federle MJ, Pompeani AJ, Kelly RC, Swem DL, Jeffrey PD, Bassler BL, Hughson FM. Neiditch MB, et al. Among authors: jeffrey pd. Cell. 2006 Sep 22;126(6):1095-108. doi: 10.1016/j.cell.2006.07.032. Cell. 2006. PMID: 16990134 Free PMC article.

7

Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*.

Baker RW, Jeffrey PD, Hughson FM. Baker RW, et al. Among authors: jeffrey pd. PLoS One. 2013 Jun 26;8(6):e67409. doi: 10.1371/journal.pone.0067409. Print 2013. PLoS One. 2013. PMID: 23840694 Free PMC article.

8

Identification of a Molecular Latch that Regulates Staphylococcal Virulence.

Xie Q, Zhao A, Jeffrey PD, Kim MK, Bassler BL, Stone HA, Novick RP, Muir TW. Xie Q, et al. Among authors: jeffrey pd. Cell Chem Biol. 2019 Apr 18;26(4):548-558.e4. doi: 10.1016/j.chembiol.2019.01.006. Epub 2019 Feb 14. Cell Chem Biol. 2019. PMID: 30773482 Free PMC article.

9

The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against Pseudomonas aeruginosa.

Taylor IR, Jeffrey PD, Moustafa DA, Goldberg JB, Bassler BL. Taylor IR, et al. Among authors: jeffrey pd. Biochemistry. 2022 Sep 6;61(17):1894-1903. doi: 10.1021/acs.biochem.2c00334. Epub 2022 Aug 19. Biochemistry. 2022. PMID: 35985643 Free PMC article.

10

Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.

Tripathi A, Ren Y, Jeffrey PD, Hughson FM. Tripathi A, et al. Among authors: jeffrey pd. Nat Struct Mol Biol. 2009 Feb;16(2):114-23. doi: 10.1038/nsmb.1548. Epub 2009 Jan 18. Nat Struct Mol Biol. 2009. PMID: 19151722 Free PMC article.

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