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p53 plays a crucial role in endothelial dysfunction associated with hyperglycemia and ischemia.
Yokoyama M, Shimizu I, Nagasawa A, Yoshida Y, Katsuumi G, Wakasugi T, Hayashi Y, Ikegami R, Suda M, Ota Y, Okada S, Fruttiger M, Kobayashi Y, Tsuchida M, Kubota Y, Minamino T. Yokoyama M, et al. Among authors: kobayashi y. J Mol Cell Cardiol. 2019 Apr;129:105-117. doi: 10.1016/j.yjmcc.2019.02.010. Epub 2019 Feb 18. J Mol Cell Cardiol. 2019. PMID: 30790589
Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization.
Tateno K, Minamino T, Toko H, Akazawa H, Shimizu N, Takeda S, Kunieda T, Miyauchi H, Oyama T, Matsuura K, Nishi J, Kobayashi Y, Nagai T, Kuwabara Y, Iwakura Y, Nomura F, Saito Y, Komuro I. Tateno K, et al. Among authors: kobayashi y. Circ Res. 2006 May 12;98(9):1194-202. doi: 10.1161/01.RES.0000219901.13974.15. Epub 2006 Mar 30. Circ Res. 2006. PMID: 16574905
Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway.
Okada S, Yokoyama M, Toko H, Tateno K, Moriya J, Shimizu I, Nojima A, Ito T, Yoshida Y, Kobayashi Y, Katagiri H, Minamino T, Komuro I. Okada S, et al. Among authors: kobayashi y. Arterioscler Thromb Vasc Biol. 2012 Aug;32(8):1902-9. doi: 10.1161/ATVBAHA.112.248930. Epub 2012 May 3. Arterioscler Thromb Vasc Biol. 2012. PMID: 22556331
Notch activation mediates angiotensin II-induced vascular remodeling by promoting the proliferation and migration of vascular smooth muscle cells.
Ozasa Y, Akazawa H, Qin Y, Tateno K, Ito K, Kudo-Sakamoto Y, Yano M, Yabumoto C, Naito AT, Oka T, Lee JK, Minamino T, Nagai T, Kobayashi Y, Komuro I. Ozasa Y, et al. Among authors: kobayashi y. Hypertens Res. 2013 Oct;36(10):859-65. doi: 10.1038/hr.2013.52. Epub 2013 May 30. Hypertens Res. 2013. PMID: 23719127
Haploinsufficiency of akt1 prolongs the lifespan of mice.
Nojima A, Yamashita M, Yoshida Y, Shimizu I, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Ishii N, Minamino T. Nojima A, et al. Among authors: kobayashi y. PLoS One. 2013 Jul 30;8(7):e69178. doi: 10.1371/journal.pone.0069178. Print 2013. PLoS One. 2013. PMID: 23935948 Free PMC article.
Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.
Yokoyama M, Okada S, Nakagomi A, Moriya J, Shimizu I, Nojima A, Yoshida Y, Ichimiya H, Kamimura N, Kobayashi Y, Ohta S, Fruttiger M, Lozano G, Minamino T. Yokoyama M, et al. Among authors: kobayashi y. Cell Rep. 2014 Jun 12;7(5):1691-1703. doi: 10.1016/j.celrep.2014.04.046. Epub 2014 May 22. Cell Rep. 2014. PMID: 24857662 Free article.
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