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Epithelial endoplasmic reticulum stress orchestrates a protective IgA response.
Grootjans J, Krupka N, Hosomi S, Matute JD, Hanley T, Saveljeva S, Gensollen T, Heijmans J, Li H, Limenitakis JP, Ganal-Vonarburg SC, Suo S, Luoma AM, Shimodaira Y, Duan J, Shih DQ, Conner ME, Glickman JN, Fuhler GM, Palm NW, de Zoete MR, van der Woude CJ, Yuan GC, Wucherpfennig KW, Targan SR, Rosenstiel P, Flavell RA, McCoy KD, Macpherson AJ, Kaser A, Blumberg RS. Grootjans J, et al. Among authors: hosomi s. Science. 2019 Mar 1;363(6430):993-998. doi: 10.1126/science.aat7186. Science. 2019. PMID: 30819965 Free PMC article.
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.
Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, Gerber G, Huang YH, Hosomi S, Arthur JC, Dery KJ, Nagaishi T, Beauchemin N, Holmes KV, Ho JW, Shively JE, Jobin C, Onderdonk AB, Bry L, Weiner HL, Higgins DE, Blumberg RS. Chen L, et al. Among authors: hosomi s. Immunity. 2012 Nov 16;37(5):930-46. doi: 10.1016/j.immuni.2012.07.016. Epub 2012 Nov 1. Immunity. 2012. PMID: 23123061 Free PMC article.
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells.
Niederreiter L, Fritz TM, Adolph TE, Krismer AM, Offner FA, Tschurtschenthaler M, Flak MB, Hosomi S, Tomczak MF, Kaneider NC, Sarcevic E, Kempster SL, Raine T, Esser D, Rosenstiel P, Kohno K, Iwawaki T, Tilg H, Blumberg RS, Kaser A. Niederreiter L, et al. Among authors: hosomi s. J Exp Med. 2013 Sep 23;210(10):2041-56. doi: 10.1084/jem.20122341. Epub 2013 Sep 16. J Exp Med. 2013. PMID: 24043762 Free PMC article.
Paneth cells as a site of origin for intestinal inflammation.
Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS. Adolph TE, et al. Among authors: hosomi s. Nature. 2013 Nov 14;503(7475):272-6. doi: 10.1038/nature12599. Epub 2013 Oct 2. Nature. 2013. PMID: 24089213 Free PMC article.
Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation.
Kubota M, Kakimoto K, Nakagawa T, Koubayashi E, Nakazawa K, Tawa H, Hirata Y, Okada T, Kawakami K, Asai A, Hosomi S, Takeuchi T, Fukunishi S, Inoue T, Asahi M, Higuchi K. Kubota M, et al. Among authors: hosomi s. PLoS One. 2019 Nov 8;14(11):e0225066. doi: 10.1371/journal.pone.0225066. eCollection 2019. PLoS One. 2019. PMID: 31703091 Free PMC article.
182 results