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Mechanisms of soft and hard electrophile toxicities.
LoPachin RM, Geohagen BC, Nordstroem LU. LoPachin RM, et al. Among authors: nordstroem lu. Toxicology. 2019 Apr 15;418:62-69. doi: 10.1016/j.tox.2019.02.005. Epub 2019 Feb 28. Toxicology. 2019. PMID: 30826385 Free PMC article. Review.
Enolate-forming compounds provide protection from platinum neurotoxicity.
Geohagen BC, Weiser DA, Loeb DM, Nordstroem LU, LoPachin RM. Geohagen BC, et al. Among authors: nordstroem lu. Chem Biol Interact. 2020 Feb 1;317:108961. doi: 10.1016/j.cbi.2020.108961. Epub 2020 Jan 21. Chem Biol Interact. 2020. PMID: 31978392 Free PMC article.
Phloretin cytoprotection and toxicity.
Geohagen BC, Korsharskyy B, Vydyanatha A, Nordstroem L, LoPachin RM. Geohagen BC, et al. Chem Biol Interact. 2018 Dec 25;296:117-123. doi: 10.1016/j.cbi.2018.09.020. Epub 2018 Oct 1. Chem Biol Interact. 2018. PMID: 30287234 Free PMC article.
Targeting the pregnane X receptor using microbial metabolite mimicry.
Dvořák Z, Kopp F, Costello CM, Kemp JS, Li H, Vrzalová A, Štěpánková M, Bartoňková I, Jiskrová E, Poulíková K, Vyhlídalová B, Nordstroem LU, Karunaratne CV, Ranhotra HS, Mun KS, Naren AP, Murray IA, Perdew GH, Brtko J, Toporova L, Schön A, Wallace BD, Walton WG, Redinbo MR, Sun K, Beck A, Kortagere S, Neary MC, Chandran A, Vishveshwara S, Cavalluzzi MM, Lentini G, Cui JY, Gu H, March JC, Chatterjee S, Matson A, Wright D, Flannigan KL, Hirota SA, Sartor RB, Mani S. Dvořák Z, et al. Among authors: nordstroem lu. EMBO Mol Med. 2020 Apr 7;12(4):e11621. doi: 10.15252/emmm.201911621. Epub 2020 Mar 10. EMBO Mol Med. 2020. PMID: 32153125 Free PMC article.