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5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma.
Kahl DJ, Hutchings KM, Lisabeth EM, Haak AJ, Leipprandt JR, Dexheimer T, Khanna D, Tsou PS, Campbell PL, Fox DA, Wen B, Sun D, Bailie M, Neubig RR, Larsen SD. Kahl DJ, et al. Among authors: campbell pl. J Med Chem. 2019 May 9;62(9):4350-4369. doi: 10.1021/acs.jmedchem.8b01772. Epub 2019 Apr 18. J Med Chem. 2019. PMID: 30951312 Free PMC article.
A novel role for inducible Fut2 in angiogenesis.
Tsou PS, Ruth JH, Campbell PL, Isozaki T, Lee S, Marotte H, Domino SE, Koch AE, Amin MA. Tsou PS, et al. Among authors: campbell pl. Angiogenesis. 2013 Jan;16(1):195-205. doi: 10.1007/s10456-012-9312-y. Epub 2012 Oct 12. Angiogenesis. 2013. PMID: 23065099 Free PMC article.
Fucosyltransferase 1 mediates angiogenesis in rheumatoid arthritis.
Isozaki T, Amin MA, Ruth JH, Campbell PL, Tsou PS, Ha CM, Stinson WA, Domino SE, Koch AE. Isozaki T, et al. Among authors: campbell pl. Arthritis Rheumatol. 2014 Aug;66(8):2047-58. doi: 10.1002/art.38648. Arthritis Rheumatol. 2014. PMID: 24692243 Free PMC article.
Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines.
Tsou PS, Rabquer BJ, Ohara RA, Stinson WA, Campbell PL, Amin MA, Balogh B, Zakhem G, Renauer PA, Lozier A, Arasu E, Haines GK 3rd, Kahaleh B, Schiopu E, Khanna D, Koch AE. Tsou PS, et al. Among authors: campbell pl. Rheumatology (Oxford). 2016 Apr;55(4):745-54. doi: 10.1093/rheumatology/kev399. Epub 2015 Dec 24. Rheumatology (Oxford). 2016. PMID: 26705326 Free PMC article.
Pharmacokinetic optimitzation of CCG-203971: Novel inhibitors of the Rho/MRTF/SRF transcriptional pathway as potential antifibrotic therapeutics for systemic scleroderma.
Hutchings KM, Lisabeth EM, Rajeswaran W, Wilson MW, Sorenson RJ, Campbell PL, Ruth JH, Amin A, Tsou PS, Leipprandt JR, Olson SR, Wen B, Zhao T, Sun D, Khanna D, Fox DA, Neubig RR, Larsen SD. Hutchings KM, et al. Among authors: campbell pl. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1744-1749. doi: 10.1016/j.bmcl.2017.02.070. Epub 2017 Mar 10. Bioorg Med Chem Lett. 2017. PMID: 28285914 Free PMC article.
Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease.
Totzke J, Gurbani D, Raphemot R, Hughes PF, Bodoor K, Carlson DA, Loiselle DR, Bera AK, Eibschutz LS, Perkins MM, Eubanks AL, Campbell PL, Fox DA, Westover KD, Haystead TAJ, Derbyshire ER. Totzke J, et al. Among authors: campbell pl. Cell Chem Biol. 2017 Aug 17;24(8):1029-1039.e7. doi: 10.1016/j.chembiol.2017.07.011. Cell Chem Biol. 2017. PMID: 28820959 Free PMC article.
A unique role for galectin-9 in angiogenesis and inflammatory arthritis.
O'Brien MJ, Shu Q, Stinson WA, Tsou PS, Ruth JH, Isozaki T, Campbell PL, Ohara RA, Koch AE, Fox DA, Amin MA. O'Brien MJ, et al. Among authors: campbell pl. Arthritis Res Ther. 2018 Feb 12;20(1):31. doi: 10.1186/s13075-018-1519-x. Arthritis Res Ther. 2018. PMID: 29433546 Free PMC article.
66 results