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5-Aryl-1,3,4-oxadiazol-2-ylthioalkanoic Acids: A Highly Potent New Class of Inhibitors of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription as Potential Antifibrotic Agents for Scleroderma.
J Med Chem. 2019 May 9;62(9):4350-4369. doi: 10.1021/acs.jmedchem.8b01772. Epub 2019 Apr 18.
J Med Chem. 2019.
PMID: 30951312
Free PMC article.
Identification of Pirin as a Molecular Target of the CCG-1423/CCG-203971 Series of Antifibrotic and Antimetastatic Compounds.
Lisabeth EM, Kahl D, Gopallawa I, Haynes SE, Misek SA, Campbell PL, Dexheimer TS, Khanna D, Fox DA, Jin X, Martin BR, Larsen SD, Neubig RR.
Lisabeth EM, et al.
ACS Pharmacol Transl Sci. 2019 Apr 12;2(2):92-100. doi: 10.1021/acsptsci.8b00048. Epub 2019 Mar 18.
ACS Pharmacol Transl Sci. 2019.
PMID: 32039344
Free PMC article.
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