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Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age.
Denegri M, Bongianino R, Lodola F, Boncompagni S, De Giusti VC, Avelino-Cruz JE, Liu N, Persampieri S, Curcio A, Esposito F, Pietrangelo L, Marty I, Villani L, Moyaho A, Baiardi P, Auricchio A, Protasi F, Napolitano C, Priori SG. Denegri M, et al. Among authors: pietrangelo l. Circulation. 2014 Jun 24;129(25):2673-81. doi: 10.1161/CIRCULATIONAHA.113.006901. Epub 2014 Jun 2. Circulation. 2014. PMID: 24888331 Free article.
Muscle Expression of SOD1G93A Triggers the Dismantlement of Neuromuscular Junction via PKC-Theta.
Dobrowolny G, Martini M, Scicchitano BM, Romanello V, Boncompagni S, Nicoletti C, Pietrangelo L, De Panfilis S, Catizone A, Bouchè M, Sandri M, Rudolf R, Protasi F, Musarò A. Dobrowolny G, et al. Among authors: pietrangelo l. Antioxid Redox Signal. 2018 Apr 20;28(12):1105-1119. doi: 10.1089/ars.2017.7054. Epub 2017 Oct 30. Antioxid Redox Signal. 2018. PMID: 28931313
Deletion of the microtubule-associated protein 6 (MAP6) results in skeletal muscle dysfunction.
Sébastien M, Giannesini B, Aubin P, Brocard J, Chivet M, Pietrangelo L, Boncompagni S, Bosc C, Brocard J, Rendu J, Gory-Fauré S, Andrieux A, Fourest-Lieuvin A, Fauré J, Marty I. Sébastien M, et al. Among authors: pietrangelo l. Skelet Muscle. 2018 Sep 19;8(1):30. doi: 10.1186/s13395-018-0176-8. Skelet Muscle. 2018. PMID: 30231928 Free PMC article.
59 results