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PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.
Zinker BA, Rondinone CM, Trevillyan JM, Gum RJ, Clampit JE, Waring JF, Xie N, Wilcox D, Jacobson P, Frost L, Kroeger PE, Reilly RM, Koterski S, Opgenorth TJ, Ulrich RG, Crosby S, Butler M, Murray SF, McKay RA, Bhanot S, Monia BP, Jirousek MR. Zinker BA, et al. Among authors: murray sf. Proc Natl Acad Sci U S A. 2002 Aug 20;99(17):11357-62. doi: 10.1073/pnas.142298199. Epub 2002 Aug 8. Proc Natl Acad Sci U S A. 2002. PMID: 12169659 Free PMC article.
miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting.
Esau C, Davis S, Murray SF, Yu XX, Pandey SK, Pear M, Watts L, Booten SL, Graham M, McKay R, Subramaniam A, Propp S, Lollo BA, Freier S, Bennett CF, Bhanot S, Monia BP. Esau C, et al. Among authors: murray sf. Cell Metab. 2006 Feb;3(2):87-98. doi: 10.1016/j.cmet.2006.01.005. Cell Metab. 2006. PMID: 16459310 Free article.
Specific reduction of hepatic glucose 6-phosphate transporter-1 ameliorates diabetes while avoiding complications of glycogen storage disease.
Sloop KW, Showalter AD, Cox AL, Cao JX, Siesky AM, Zhang HY, Irizarry AR, Murray SF, Booten SL, Finger EA, McKay RA, Monia BP, Bhanot S, Michael MD. Sloop KW, et al. Among authors: murray sf. J Biol Chem. 2007 Jun 29;282(26):19113-21. doi: 10.1074/jbc.M610759200. Epub 2007 May 3. J Biol Chem. 2007. PMID: 17478431 Free article.
104 results