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Discovery of novel steroidal histamine H3 receptor antagonists/inverse agonists.
Ledneczki I, Tapolcsányi P, Gábor E, Éles J, Greiner I, Schmidt É, Némethy Z, Kedves RS, Balázs O, Román V, Lévay G, Mahó S. Ledneczki I, et al. Among authors: kedves rs. Bioorg Med Chem Lett. 2017 Oct 1;27(19):4525-4530. doi: 10.1016/j.bmcl.2017.08.060. Epub 2017 Sep 1. Bioorg Med Chem Lett. 2017. PMID: 28888822
Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15.
Gyertyán I, Sághy K, Laszy J, Elekes O, Kedves R, Gémesi LI, Pásztor G, Zájer-Balázs M, Kapás M, Agai Csongor E, Domány G, Kiss B, Szombathelyi Z. Gyertyán I, et al. Among authors: kedves r. Naunyn Schmiedebergs Arch Pharmacol. 2008 Nov;378(5):529-39. doi: 10.1007/s00210-008-0311-x. Epub 2008 Jun 12. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18548231
The influence of 5-HT(2A) activity on a 5-HT(2C) specific in vivo assay used for early identification of multiple acting SERT and 5-HT(2C) receptor ligands.
Éliás O, Nógrádi K, Domány G, Szakács Z, Kóti J, Szántay C Jr, Tarcsay Á, Keserű GM, Gere A, Kiss B, Kurkó D, Kolok S, Némethy Z, Kapui Z, Hellinger É, Vastag M, Sághy K, Kedves R, Gyertyán I. Éliás O, et al. Among authors: kedves r. Bioorg Med Chem Lett. 2016 Feb 1;26(3):914-920. doi: 10.1016/j.bmcl.2015.12.071. Epub 2015 Dec 21. Bioorg Med Chem Lett. 2016. PMID: 26748694
Selective interaction of homophtalazine derivatives with morphine.
Fekete MI, Horváth K, Kedves R, Máté I, Székely JI, Szentkuti E. Fekete MI, et al. Among authors: kedves r. Eur J Pharmacol. 1997 Jul 23;331(2-3):175-83. doi: 10.1016/s0014-2999(97)01056-x. Eur J Pharmacol. 1997. PMID: 9274977
11 results