Keightley PD - Search Results

1

Inferring the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii.

Böndel KB, Kraemer SA, Samuels T, McClean D, Lachapelle J, Ness RW, Colegrave N, Keightley PD. Böndel KB, et al. Among authors: keightley pd. PLoS Biol. 2019 Jun 26;17(6):e3000192. doi: 10.1371/journal.pbio.3000192. eCollection 2019 Jun. PLoS Biol. 2019. PMID: 31242179 Free PMC article.

2

Toward a realistic model of mutations affecting fitness.

Keightley PD, Lynch M. Keightley PD, et al. Evolution. 2003 Mar;57(3):683-5; discussion 686-9. doi: 10.1111/j.0014-3820.2003.tb01561.x. Evolution. 2003. PMID: 12703958

3

Regulatory variation at glypican-3 underlies a major growth QTL in mice.

Oliver F, Christians JK, Liu X, Rhind S, Verma V, Davison C, Brown SD, Denny P, Keightley PD. Oliver F, et al. Among authors: keightley pd. PLoS Biol. 2005 May;3(5):e135. doi: 10.1371/journal.pbio.0030135. Epub 2005 Apr 5. PLoS Biol. 2005. PMID: 15799711 Free PMC article.

4

Joint inference of the distribution of fitness effects of deleterious mutations and population demography based on nucleotide polymorphism frequencies.

Keightley PD, Eyre-Walker A. Keightley PD, et al. Genetics. 2007 Dec;177(4):2251-61. doi: 10.1534/genetics.107.080663. Genetics. 2007. PMID: 18073430 Free PMC article.

5

Direct estimation of the mitochondrial DNA mutation rate in Drosophila melanogaster.

Haag-Liautard C, Coffey N, Houle D, Lynch M, Charlesworth B, Keightley PD. Haag-Liautard C, et al. Among authors: keightley pd. PLoS Biol. 2008 Aug 19;6(8):e204. doi: 10.1371/journal.pbio.0060204. PLoS Biol. 2008. PMID: 18715119 Free PMC article.

6

Evidence for pervasive adaptive protein evolution in wild mice.

Halligan DL, Oliver F, Eyre-Walker A, Harr B, Keightley PD. Halligan DL, et al. Among authors: keightley pd. PLoS Genet. 2010 Jan 22;6(1):e1000825. doi: 10.1371/journal.pgen.1000825. PLoS Genet. 2010. PMID: 20107605 Free PMC article.

7

The role of advantageous mutations in enhancing the evolution of a recombination modifier.

Hartfield M, Otto SP, Keightley PD. Hartfield M, et al. Among authors: keightley pd. Genetics. 2010 Apr;184(4):1153-64. doi: 10.1534/genetics.109.112920. Epub 2010 Feb 5. Genetics. 2010. PMID: 20139345 Free PMC article.

8

What can we learn about the distribution of fitness effects of new mutations from DNA sequence data?

Keightley PD, Eyre-Walker A. Keightley PD, et al. Philos Trans R Soc Lond B Biol Sci. 2010 Apr 27;365(1544):1187-93. doi: 10.1098/rstb.2009.0266. Philos Trans R Soc Lond B Biol Sci. 2010. PMID: 20308093 Free PMC article.

9

Positive and negative selection in murine ultraconserved noncoding elements.

Halligan DL, Oliver F, Guthrie J, Stemshorn KC, Harr B, Keightley PD. Halligan DL, et al. Among authors: keightley pd. Mol Biol Evol. 2011 Sep;28(9):2651-60. doi: 10.1093/molbev/msr093. Epub 2011 Apr 8. Mol Biol Evol. 2011. PMID: 21478460

10

A method for inferring the rate of occurrence and fitness effects of advantageous mutations.

Schneider A, Charlesworth B, Eyre-Walker A, Keightley PD. Schneider A, et al. Among authors: keightley pd. Genetics. 2011 Dec;189(4):1427-37. doi: 10.1534/genetics.111.131730. Epub 2011 Sep 27. Genetics. 2011. PMID: 21954160 Free PMC article.

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