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Investigation of betaine as a novel psychotherapeutic for schizophrenia.
Ohnishi T, Balan S, Toyoshima M, Maekawa M, Ohba H, Watanabe A, Iwayama Y, Fujita Y, Tan Y, Hisano Y, Shimamoto-Mitsuyama C, Nozaki Y, Esaki K, Nagaoka A, Matsumoto J, Hino M, Mataga N, Hayashi-Takagi A, Hashimoto K, Kunii Y, Kakita A, Yabe H, Yoshikawa T. Ohnishi T, et al. Among authors: watanabe a. EBioMedicine. 2019 Jul;45:432-446. doi: 10.1016/j.ebiom.2019.05.062. Epub 2019 Jun 26. EBioMedicine. 2019. PMID: 31255657 Free PMC article.
Peroxisome proliferator-activated receptor α as a novel therapeutic target for schizophrenia.
Wada Y, Maekawa M, Ohnishi T, Balan S, Matsuoka S, Iwamoto K, Iwayama Y, Ohba H, Watanabe A, Hisano Y, Nozaki Y, Toyota T, Shimogori T, Itokawa M, Kobayashi T, Yoshikawa T. Wada Y, et al. Among authors: watanabe a. EBioMedicine. 2020 Dec;62:103130. doi: 10.1016/j.ebiom.2020.103130. Epub 2020 Dec 2. EBioMedicine. 2020. PMID: 33279456 Free PMC article.
Fabp7 maps to a quantitative trait locus for a schizophrenia endophenotype.
Watanabe A, Toyota T, Owada Y, Hayashi T, Iwayama Y, Matsumata M, Ishitsuka Y, Nakaya A, Maekawa M, Ohnishi T, Arai R, Sakurai K, Yamada K, Kondo H, Hashimoto K, Osumi N, Yoshikawa T. Watanabe A, et al. PLoS Biol. 2007 Nov;5(11):e297. doi: 10.1371/journal.pbio.0050297. PLoS Biol. 2007. PMID: 18001149 Free PMC article.
Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies.
Shimamoto C, Ohnishi T, Maekawa M, Watanabe A, Ohba H, Arai R, Iwayama Y, Hisano Y, Toyota T, Toyoshima M, Suzuki K, Shirayama Y, Nakamura K, Mori N, Owada Y, Kobayashi T, Yoshikawa T. Shimamoto C, et al. Among authors: watanabe a. Hum Mol Genet. 2014 Dec 15;23(24):6495-511. doi: 10.1093/hmg/ddu369. Epub 2014 Jul 15. Hum Mol Genet. 2014. PMID: 25027319 Free PMC article.
Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology.
Ide M, Ohnishi T, Toyoshima M, Balan S, Maekawa M, Shimamoto-Mitsuyama C, Iwayama Y, Ohba H, Watanabe A, Ishii T, Shibuya N, Kimura Y, Hisano Y, Murata Y, Hara T, Morikawa M, Hashimoto K, Nozaki Y, Toyota T, Wada Y, Tanaka Y, Kato T, Nishi A, Fujisawa S, Okano H, Itokawa M, Hirokawa N, Kunii Y, Kakita A, Yabe H, Iwamoto K, Meno K, Katagiri T, Dean B, Uchida K, Kimura H, Yoshikawa T. Ide M, et al. Among authors: watanabe a. EMBO Mol Med. 2019 Dec;11(12):e10695. doi: 10.15252/emmm.201910695. Epub 2019 Oct 28. EMBO Mol Med. 2019. PMID: 31657521 Free PMC article.
Role of an Atypical Cadherin Gene, Cdh23 in Prepulse Inhibition, and Implication of CDH23 in Schizophrenia.
Balan S, Ohnishi T, Watanabe A, Ohba H, Iwayama Y, Toyoshima M, Hara T, Hisano Y, Miyasaka Y, Toyota T, Shimamoto-Mitsuyama C, Maekawa M, Numata S, Ohmori T, Shimogori T, Kikkawa Y, Hayashi T, Yoshikawa T. Balan S, et al. Among authors: watanabe a. Schizophr Bull. 2021 Jul 8;47(4):1190-1200. doi: 10.1093/schbul/sbab007. Schizophr Bull. 2021. PMID: 33595068 Free PMC article.
Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes.
Maekawa M, Watanabe A, Iwayama Y, Kimura T, Hamazaki K, Balan S, Ohba H, Hisano Y, Nozaki Y, Ohnishi T, Toyoshima M, Shimamoto C, Iwamoto K, Bundo M, Osumi N, Takahashi E, Takashima A, Yoshikawa T. Maekawa M, et al. Among authors: watanabe a. Transl Psychiatry. 2017 Sep 5;7(9):e1229. doi: 10.1038/tp.2017.182. Transl Psychiatry. 2017. PMID: 28872641 Free PMC article.
4,647 results