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Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation.
Lowery J, Szul T, Seetharaman J, Jian X, Su M, Forouhar F, Xiao R, Acton TB, Montelione GT, Lin H, Wright JW, Lee E, Holloway ZG, Randazzo PA, Tong L, Sztul E. Lowery J, et al. Among authors: lee e. J Biol Chem. 2011 Oct 21;286(42):36898-906. doi: 10.1074/jbc.M111.230631. Epub 2011 Aug 2. J Biol Chem. 2011. PMID: 21828055 Free PMC article.
Oligomerization of the Sec7 domain Arf guanine nucleotide exchange factor GBF1 is dispensable for Golgi localization and function but regulates degradation.
Bhatt JM, Viktorova EG, Busby T, Wyrozumska P, Newman LE, Lin H, Lee E, Wright J, Belov GA, Kahn RA, Sztul E. Bhatt JM, et al. Among authors: lee e. Am J Physiol Cell Physiol. 2016 Mar 15;310(6):C456-69. doi: 10.1152/ajpcell.00185.2015. Epub 2015 Dec 30. Am J Physiol Cell Physiol. 2016. PMID: 26718629 Free PMC article.
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