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Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.
Frendo-Cumbo S, Jaldin-Fincati JR, Coyaud E, Laurent EMN, Townsend LK, Tan JMJ, Xavier RJ, Pillon NJ, Raught B, Wright DC, Brumell JH, Klip A. Frendo-Cumbo S, et al. Among authors: jaldin fincati jr. J Biol Chem. 2019 Nov 1;294(44):16172-16185. doi: 10.1074/jbc.RA119.009110. Epub 2019 Sep 12. J Biol Chem. 2019. PMID: 31515271 Free PMC article.
Update on GLUT4 Vesicle Traffic: A Cornerstone of Insulin Action.
Jaldin-Fincati JR, Pavarotti M, Frendo-Cumbo S, Bilan PJ, Klip A. Jaldin-Fincati JR, et al. Trends Endocrinol Metab. 2017 Aug;28(8):597-611. doi: 10.1016/j.tem.2017.05.002. Epub 2017 Jun 8. Trends Endocrinol Metab. 2017. PMID: 28602209 Review.
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