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The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis.
De Luca A, Carpanese D, Rapanotti MC, Viguria TM, Forgione MA, Rotili D, Fulci C, Iorio E, Quintieri L, Chimenti S, Bianchi L, Rosato A, Caccuri AM. De Luca A, et al. Among authors: caccuri am. Oncotarget. 2017 Feb 28;8(9):15520-15538. doi: 10.18632/oncotarget.14690. Oncotarget. 2017. PMID: 28107182 Free PMC article.
Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis.
Di Paolo V, Fulci C, Rotili D, Sciarretta F, Lucidi A, Morozzo Della Rocca B, De Luca A, Rosato A, Quintieri L, Caccuri AM. Di Paolo V, et al. Among authors: caccuri am. J Enzyme Inhib Med Chem. 2019 Dec;34(1):1131-1139. doi: 10.1080/14756366.2019.1617287. J Enzyme Inhib Med Chem. 2019. PMID: 31169043 Free PMC article.
Glutathione S-transferase P1-1 as a target for mesothelioma treatment.
De Luca A, Pellizzari Tregno F, Sau A, Pastore A, Palumbo C, Alama A, Cicconi R, Federici G, Caccuri AM. De Luca A, et al. Among authors: caccuri am. Cancer Sci. 2013 Feb;104(2):223-30. doi: 10.1111/cas.12061. Epub 2012 Dec 24. Cancer Sci. 2013. PMID: 23121163 Free PMC article.
A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts.
De Luca A, Rotili D, Carpanese D, Lenoci A, Calderan L, Scimeca M, Mai A, Bonanno E, Rosato A, Geroni C, Quintieri L, Caccuri AM. De Luca A, et al. Among authors: caccuri am. Oncotarget. 2015 Feb 28;6(6):4126-43. doi: 10.18632/oncotarget.2798. Oncotarget. 2015. PMID: 25595904 Free PMC article.
96 results