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Page 1
Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells.
Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M. Frodermann V, et al. Among authors: mcalpine cs. Nat Med. 2019 Nov;25(11):1761-1771. doi: 10.1038/s41591-019-0633-x. Epub 2019 Nov 7. Nat Med. 2019. PMID: 31700184 Free PMC article.
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver.
Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK. Theurl I, et al. Nat Med. 2016 Aug;22(8):945-51. doi: 10.1038/nm.4146. Epub 2016 Jul 18. Nat Med. 2016. PMID: 27428900 Free PMC article.
The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes.
Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK. Anzai A, et al. Among authors: mcalpine cs. J Exp Med. 2017 Nov 6;214(11):3293-3310. doi: 10.1084/jem.20170689. Epub 2017 Oct 4. J Exp Med. 2017. PMID: 28978634 Free PMC article.
Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis.
Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK. Anzai A, et al. Among authors: mcalpine cs. J Exp Med. 2019 Feb 4;216(2):369-383. doi: 10.1084/jem.20180722. Epub 2019 Jan 22. J Exp Med. 2019. PMID: 30670465 Free PMC article.
Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease.
He S, Kahles F, Rattik S, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK. He S, et al. Among authors: mcalpine cs. Nature. 2019 Feb;566(7742):115-119. doi: 10.1038/s41586-018-0849-9. Epub 2019 Jan 30. Nature. 2019. PMID: 30700910 Free PMC article.
Sleep modulates haematopoiesis and protects against atherosclerosis.
McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK. McAlpine CS, et al. Nature. 2019 Feb;566(7744):383-387. doi: 10.1038/s41586-019-0948-2. Epub 2019 Feb 13. Nature. 2019. PMID: 30760925 Free PMC article.
Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes Mellitus.
Hoyer FF, Zhang X, Coppin E, Vasamsetti SB, Modugu G, Schloss MJ, Rohde D, McAlpine CS, Iwamoto Y, Libby P, Naxerova K, Swirski FK, Dutta P, Nahrendorf M. Hoyer FF, et al. Among authors: mcalpine cs. Circulation. 2020 Jul 21;142(3):244-258. doi: 10.1161/CIRCULATIONAHA.120.046038. Epub 2020 Apr 22. Circulation. 2020. PMID: 32316750 Free PMC article.
Liver X receptors are required for thymic resilience and T cell output.
Chan CT, Fenn AM, Harder NK, Mindur JE, McAlpine CS, Patel J, Valet C, Rattik S, Iwamoto Y, He S, Anzai A, Kahles F, Poller WC, Janssen H, Wong LP, Fernandez-Hernando C, Koolbergen DR, van der Laan AM, Yvan-Charvet L, Sadreyev RI, Nahrendorf M, Westerterp M, Tall AR, Gustafsson JA, Swirski FK. Chan CT, et al. Among authors: mcalpine cs. J Exp Med. 2020 Oct 5;217(10):e20200318. doi: 10.1084/jem.20200318. J Exp Med. 2020. PMID: 32716519 Free PMC article.
Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis.
Heyde A, Rohde D, McAlpine CS, Zhang S, Hoyer FF, Gerold JM, Cheek D, Iwamoto Y, Schloss MJ, Vandoorne K, Iborra-Egea O, Muñoz-Guijosa C, Bayes-Genis A, Reiter JG, Craig M, Swirski FK, Nahrendorf M, Nowak MA, Naxerova K. Heyde A, et al. Among authors: mcalpine cs. Cell. 2021 Mar 4;184(5):1348-1361.e22. doi: 10.1016/j.cell.2021.01.049. Epub 2021 Feb 25. Cell. 2021. PMID: 33636128 Free PMC article.
34 results