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Discovery of a Potent and Selective TRPC5 Inhibitor, Efficacious in a Focal Segmental Glomerulosclerosis Model.
Yu M, Ledeboer MW, Daniels M, Malojcic G, Tibbitts TT, Coeffet-Le Gal M, Pan-Zhou XR, Westerling-Bui A, Beconi M, Reilly JF, Mundel P, Harmange JC. Yu M, et al. Among authors: mundel p. ACS Med Chem Lett. 2019 Oct 22;10(11):1579-1585. doi: 10.1021/acsmedchemlett.9b00430. eCollection 2019 Nov 14. ACS Med Chem Lett. 2019. PMID: 31749913 Free PMC article.
Transplanted organoids empower human preclinical assessment of drug candidate for the clinic.
Westerling-Bui AD, Fast EM, Soare TW, Venkatachalan S, DeRan M, Fanelli AB, Kyrychenko S, Hoang H, Corriea GM, Zhang W, Yu M, Daniels M, Malojcic G, Pan-Zhou XR, Ledeboer MW, Harmange JC, Emani M, Tibbitts TT, Reilly JF, Mundel P. Westerling-Bui AD, et al. Among authors: mundel p. Sci Adv. 2022 Jul 8;8(27):eabj5633. doi: 10.1126/sciadv.abj5633. Epub 2022 Jul 6. Sci Adv. 2022. PMID: 35857479 Free PMC article.
GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death.
Sieber J, Wieder N, Clark A, Reitberger M, Matan S, Schoenfelder J, Zhang J, Mandinova A, Bittker JA, Gutierrez J, Aygün O, Udeshi N, Carr S, Mundel P, Jehle AW, Greka A. Sieber J, et al. Among authors: mundel p. Cell Chem Biol. 2018 Feb 15;25(2):175-184.e4. doi: 10.1016/j.chembiol.2017.11.006. Epub 2017 Dec 14. Cell Chem Biol. 2018. PMID: 29249695 Free PMC article.
Proteinuria: an enzymatic disease of the podocyte?
Mundel P, Reiser J. Mundel P, et al. Kidney Int. 2010 Apr;77(7):571-80. doi: 10.1038/ki.2009.424. Epub 2009 Nov 18. Kidney Int. 2010. PMID: 19924101 Free PMC article. Review.
Podocytes in culture: past, present, and future.
Shankland SJ, Pippin JW, Reiser J, Mundel P. Shankland SJ, et al. Among authors: mundel p. Kidney Int. 2007 Jul;72(1):26-36. doi: 10.1038/sj.ki.5002291. Epub 2007 Apr 25. Kidney Int. 2007. PMID: 17457377 Free article. Review.
158 results