Kwon NH - Search Results

1

Moonlighting matrix metalloproteinase substrates: Enhancement of proinflammatory functions of extracellular tyrosyl-tRNA synthetase upon cleavage.

Jobin PG, Solis N, Machado Y, Bell PA, Rai SK, Kwon NH, Kim S, Overall CM, Butler GS. Jobin PG, et al. Among authors: kwon nh. J Biol Chem. 2020 Feb 21;295(8):2186-2202. doi: 10.1074/jbc.RA119.010486. Epub 2019 Nov 26. J Biol Chem. 2020. PMID: 31771979 Free PMC article.

2

Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase.

Jobin PG, Solis N, Machado Y, Bell PA, Kwon NH, Kim S, Overall CM, Butler GS. Jobin PG, et al. Among authors: kwon nh. J Biol Chem. 2019 Aug 30;294(35):12866-12879. doi: 10.1074/jbc.RA119.009584. Epub 2019 Jul 19. J Biol Chem. 2019. PMID: 31324718 Free PMC article.

3

Association of aminoacyl-tRNA synthetases with cancer.

Kim D, Kwon NH, Kim S. Kim D, et al. Among authors: kwon nh. Top Curr Chem. 2014;344:207-45. doi: 10.1007/128_2013_455. Top Curr Chem. 2014. PMID: 23818134 Review.

4

Suppression of lysyl-tRNA synthetase, KRS, causes incomplete epithelial-mesenchymal transition and ineffective cell‑extracellular matrix adhesion for migration.

Nam SH, Kang M, Ryu J, Kim HJ, Kim D, Kim DG, Kwon NH, Kim S, Lee JW. Nam SH, et al. Among authors: kwon nh. Int J Oncol. 2016 Apr;48(4):1553-60. doi: 10.3892/ijo.2016.3381. Epub 2016 Feb 8. Int J Oncol. 2016. PMID: 26891990

5

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.

Han JM, Jeong SJ, Park MC, Kim G, Kwon NH, Kim HK, Ha SH, Ryu SH, Kim S. Han JM, et al. Among authors: kwon nh. Cell. 2012 Apr 13;149(2):410-24. doi: 10.1016/j.cell.2012.02.044. Epub 2012 Mar 15. Cell. 2012. PMID: 22424946 Free article.

6

Aminoacyl-tRNA synthetases as therapeutic targets.

Kwon NH, Fox PL, Kim S. Kwon NH, et al. Nat Rev Drug Discov. 2019 Aug;18(8):629-650. doi: 10.1038/s41573-019-0026-3. Nat Rev Drug Discov. 2019. PMID: 31073243 Review.

7

Role of tRNAs in Breast Cancer Regulation.

Kwon NH, Lee JY, Kim S. Kwon NH, et al. Adv Exp Med Biol. 2021;1187:121-145. doi: 10.1007/978-981-32-9620-6_6. Adv Exp Med Biol. 2021. PMID: 33983576 Review.

8

Discovery of novel potent migrastatic Thiazolo[5,4-b]pyridines targeting Lysyl-tRNA synthetase (KRS) for treatment of Cancer metastasis.

Lee S, Kwon NH, Seo B, Lee JY, Cho HY, Kim K, Kim HS, Jung K, Jeon YH, Kim S, Suh YG. Lee S, et al. Among authors: kwon nh. Eur J Med Chem. 2021 Jun 5;218:113405. doi: 10.1016/j.ejmech.2021.113405. Epub 2021 Mar 30. Eur J Med Chem. 2021. PMID: 33831781

9

Methionyl-tRNA Synthetase is a Useful Diagnostic Marker for Lymph Node Metastasis in Non-Small Cell Lung Cancer.

Lee JM, Kim T, Kim EY, Kim A, Lee DK, Kwon NH, Kim S, Chang YS. Lee JM, et al. Among authors: kwon nh. Yonsei Med J. 2019 Nov;60(11):1005-1012. doi: 10.3349/ymj.2019.60.11.1005. Yonsei Med J. 2019. PMID: 31637881 Free PMC article.

10

Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection.

Ahn YH, Park S, Choi JJ, Park BK, Rhee KH, Kang E, Ahn S, Lee CH, Lee JS, Inn KS, Cho ML, Park SH, Park K, Park HJ, Lee JH, Park JW, Kwon NH, Shim H, Han BW, Kim P, Lee JY, Jeon Y, Huh JW, Jin M, Kim S. Ahn YH, et al. Among authors: kwon nh. Nat Microbiol. 2016 Oct 17;2:16191. doi: 10.1038/nmicrobiol.2016.191. Nat Microbiol. 2016. PMID: 27748732

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