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Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion.
Wienand K, Chapuy B, Stewart C, Dunford AJ, Wu D, Kim J, Kamburov A, Wood TR, Cader FZ, Ducar MD, Thorner AR, Nag A, Heubeck AT, Buonopane MJ, Redd RA, Bojarczuk K, Lawton LN, Armand P, Rodig SJ, Fromm JR, Getz G, Shipp MA. Wienand K, et al. Among authors: lawton ln. Blood Adv. 2019 Dec 10;3(23):4065-4080. doi: 10.1182/bloodadvances.2019001012. Blood Adv. 2019. PMID: 31816062 Free PMC article.
CXCR4 upregulation is an indicator of sensitivity to B-cell receptor/PI3K blockade and a potential resistance mechanism in B-cell receptor-dependent diffuse large B-cell lymphomas.
Chen L, Ouyang J, Wienand K, Bojarczuk K, Hao Y, Chapuy B, Neuberg D, Juszczynski P, Lawton LN, Rodig SJ, Monti S, Shipp MA. Chen L, et al. Among authors: lawton ln. Haematologica. 2020 May;105(5):1361-1368. doi: 10.3324/haematol.2019.216218. Epub 2019 Aug 30. Haematologica. 2020. PMID: 31471373 Free PMC article.
A peripheral immune signature of responsiveness to PD-1 blockade in patients with classical Hodgkin lymphoma.
Cader FZ, Hu X, Goh WL, Wienand K, Ouyang J, Mandato E, Redd R, Lawton LN, Chen PH, Weirather JL, Schackmann RCJ, Li B, Ma W, Armand P, Rodig SJ, Neuberg D, Liu XS, Shipp MA. Cader FZ, et al. Among authors: lawton ln. Nat Med. 2020 Sep;26(9):1468-1479. doi: 10.1038/s41591-020-1006-1. Epub 2020 Aug 10. Nat Med. 2020. PMID: 32778827 Free PMC article. Clinical Trial.
19 results