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In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects.
Osinski V, Bauknight DK, Dasa SSK, Harms MJ, Kroon T, Marshall MA, Garmey JC, Nguyen AT, Hartman J, Upadhye A, Srikakulapu P, Zhou A, O'Mahony G, Klibanov AL, Kelly KA, Boucher J, McNamara CA. Osinski V, et al. Among authors: hartman j. Theranostics. 2020 Jan 1;10(2):585-601. doi: 10.7150/thno.36572. eCollection 2020. Theranostics. 2020. PMID: 31903139 Free PMC article.
Tumor-associated NK cells drive MDSC-mediated tumor immune tolerance through the IL-6/STAT3 axis.
Neo SY, Tong L, Chong J, Liu Y, Jing X, Oliveira MMS, Chen Y, Chen Z, Lee K, Burduli N, Chen X, Gao J, Ma R, Lim JP, Huo J, Xu S, Alici E, Wickström SL, Haglund F, Hartman J, Wagner AK, Cao Y, Kiessling R, Lam KP, Westerberg LS, Lundqvist A. Neo SY, et al. Among authors: hartman j. Sci Transl Med. 2024 May 15;16(747):eadi2952. doi: 10.1126/scitranslmed.adi2952. Epub 2024 May 15. Sci Transl Med. 2024. PMID: 38748775
Real-world overall survival and characteristics of patients with ER-zero and ER-low HER2-negative breast cancer treated as triple-negative breast cancer: a Swedish population-based cohort study.
Acs B, Hartman J, Sönmez D, Lindman H, Johansson ALV, Fredriksson I. Acs B, et al. Among authors: hartman j. Lancet Reg Health Eur. 2024 Mar 19;40:100886. doi: 10.1016/j.lanepe.2024.100886. eCollection 2024 May. Lancet Reg Health Eur. 2024. PMID: 38745990 Free PMC article.
Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility.
Romero A, Ashcraft L, Chandra A, DiMassa V, Cremin P, Collibee SE, Chuang C, Hartman J, Hwee DT, St Jean D, Malinowski J, DeBenedetto M, Moebius D, Payette J, Vargas R, Yeoman J, Motani A, Reagan J, Malik FI, Morgan BP. Romero A, et al. Among authors: hartman j. J Med Chem. 2024 May 23;67(10):7825-7835. doi: 10.1021/acs.jmedchem.3c02413. Epub 2024 May 10. J Med Chem. 2024. PMID: 38729623 Free PMC article.
Impact and timing of pulmonary rehabilitation in patients undergoing bronchoscopic lung volume reduction with endobronchial valves: A multicentre randomized controlled trial in patients with severe emphysema.
van der Molen MC, Posthuma R, Hartman JE, van der Vaart H, Bij de Vaate E, Vaes AW, van den Borst B, van Ranst D, Spruit MA, Vanfleteren LEGW, Slebos DJ; SoLVE consortium group. van der Molen MC, et al. Among authors: hartman je. Respirology. 2024 May 8. doi: 10.1111/resp.14734. Online ahead of print. Respirology. 2024. PMID: 38720189
1,102 results