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Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.
Van den Bossche J, Baardman J, Otto NA, van der Velden S, Neele AE, van den Berg SM, Luque-Martin R, Chen HJ, Boshuizen MC, Ahmed M, Hoeksema MA, de Vos AF, de Winther MP. Van den Bossche J, et al. Cell Rep. 2016 Oct 11;17(3):684-696. doi: 10.1016/j.celrep.2016.09.008. Cell Rep. 2016. PMID: 27732846 Free article.
Myeloid Kdm6b deficiency results in advanced atherosclerosis.
Neele AE, Gijbels MJJ, van der Velden S, Hoeksema MA, Boshuizen MCS, Prange KHM, Chen HJ, Van den Bossche J, van Roomen CPPA, Shami A, Levels JHM, Kroon J, Lucas T, Dimmeler S, Lutgens E, de Winther MPJ. Neele AE, et al. Among authors: de winther mpj. Atherosclerosis. 2018 Aug;275:156-165. doi: 10.1016/j.atherosclerosis.2018.05.052. Epub 2018 Jun 1. Atherosclerosis. 2018. PMID: 29908485 Free article.
Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis.
Luque-Martin R, Van den Bossche J, Furze RC, Neele AE, van der Velden S, Gijbels MJJ, van Roomen CPPA, Bernard SG, de Jonge WJ, Rioja I, Prinjha RK, Lewis HD, Mander PK, de Winther MPJ. Luque-Martin R, et al. Among authors: de jonge wj, de winther mpj. Front Pharmacol. 2019 Oct 29;10:1242. doi: 10.3389/fphar.2019.01242. eCollection 2019. Front Pharmacol. 2019. PMID: 31736752 Free PMC article.
Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss.
Willemsen L, Neele AE, van der Velden S, Prange KHM, den Toom M, van Roomen CPAA, Reiche ME, Griffith GR, Gijbels MJJ, Lutgens E, de Winther MPJ. Willemsen L, et al. Among authors: de winther mpj. BMJ Open Diabetes Res Care. 2019 Nov 2;7(1):e000751. doi: 10.1136/bmjdrc-2019-000751. eCollection 2019. BMJ Open Diabetes Res Care. 2019. PMID: 31798899 Free PMC article.
Type-I interferons in atherosclerosis.
Chen HJ, Tas SW, de Winther MPJ. Chen HJ, et al. Among authors: de winther mpj. J Exp Med. 2020 Jan 6;217(1):e20190459. doi: 10.1084/jem.20190459. J Exp Med. 2020. PMID: 31821440 Free PMC article. Review.
Targeting epigenetics as atherosclerosis treatment: an updated view.
Neele AE, Willemsen L, Chen HJ, Dzobo KE, de Winther MPJ. Neele AE, et al. Among authors: de winther mpj. Curr Opin Lipidol. 2020 Dec;31(6):324-330. doi: 10.1097/MOL.0000000000000711. Curr Opin Lipidol. 2020. PMID: 33027226 Free PMC article. Review.
HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.
Ghiboub M, Zhao J, Li Yim AYF, Schilderink R, Verseijden C, van Hamersveld PHP, Duarte JM, Hakvoort TBM, Admiraal I, Harker NR, Tough DF, Henneman P, de Winther MPJ, de Jonge WJ. Ghiboub M, et al. Among authors: de jonge wj, de winther mpj. Front Immunol. 2020 Oct 5;11:550769. doi: 10.3389/fimmu.2020.550769. eCollection 2020. Front Immunol. 2020. PMID: 33123128 Free PMC article.
SIRPα on Mouse B1 Cells Restricts Lymphoid Tissue Migration and Natural Antibody Production.
Franke K, Pillai SY, Hoogenboezem M, Gijbels MJJ, Matlung HL, Geissler J, Olsman H, Pottgens C, van Gorp PJ, Ozsvar-Kozma M, Saito Y, Matozaki T, Kuijpers TW, Hendriks RW, Kraal G, Binder CJ, de Winther MPJ, van den Berg TK. Franke K, et al. Among authors: de winther mpj. Front Immunol. 2020 Oct 9;11:570963. doi: 10.3389/fimmu.2020.570963. eCollection 2020. Front Immunol. 2020. PMID: 33162986 Free PMC article.
198 results