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APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid.
Zhao N, Attrebi ON, Ren Y, Qiao W, Sonustun B, Martens YA, Meneses AD, Li F, Shue F, Zheng J, Van Ingelgom AJ, Davis MD, Kurti A, Knight JA, Linares C, Chen Y, Delenclos M, Liu CC, Fryer JD, Asmann YW, McLean PJ, Dickson DW, Ross OA, Bu G. Zhao N, et al. Among authors: mclean pj. Sci Transl Med. 2020 Feb 5;12(529):eaay1809. doi: 10.1126/scitranslmed.aay1809. Sci Transl Med. 2020. PMID: 32024798 Free PMC article.
Alpha-synuclein and tau: teammates in neurodegeneration?
Moussaud S, Jones DR, Moussaud-Lamodière EL, Delenclos M, Ross OA, McLean PJ. Moussaud S, et al. Among authors: mclean pj. Mol Neurodegener. 2014 Oct 29;9:43. doi: 10.1186/1750-1326-9-43. Mol Neurodegener. 2014. PMID: 25352339 Free PMC article. Review.
Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice.
Yue M, Hinkle KM, Davies P, Trushina E, Fiesel FC, Christenson TA, Schroeder AS, Zhang L, Bowles E, Behrouz B, Lincoln SJ, Beevers JE, Milnerwood AJ, Kurti A, McLean PJ, Fryer JD, Springer W, Dickson DW, Farrer MJ, Melrose HL. Yue M, et al. Among authors: mclean pj. Neurobiol Dis. 2015 Jun;78:172-95. doi: 10.1016/j.nbd.2015.02.031. Epub 2015 Mar 31. Neurobiol Dis. 2015. PMID: 25836420 Free PMC article.
DNAJC13 p.Asn855Ser mutation screening in Parkinson's disease and pathologically confirmed Lewy body disease patients.
Lorenzo-Betancor O, Ogaki K, Soto-Ortolaza AI, Labbe C, Walton RL, Strongosky AJ, van Gerpen JA, Uitti RJ, McLean PJ, Springer W, Siuda J, Opala G, Krygowska-Wajs A, Barcikowska M, Czyzewski K, McCarthy A, Lynch T, Puschmann A, Rektorova I, Sanotsky Y, Vilariño-Güell C, Farrer MJ, Ferman TJ, Boeve BF, Petersen RC, Parisi JE, Graff-Radford NR, Dickson DW, Wszolek ZK, Ross OA. Lorenzo-Betancor O, et al. Among authors: mclean pj. Eur J Neurol. 2015 Sep;22(9):1323-5. doi: 10.1111/ene.12770. Eur J Neurol. 2015. PMID: 26278106 Free PMC article.
Role for the microtubule-associated protein tau variant p.A152T in risk of α-synucleinopathies.
Labbé C, Ogaki K, Lorenzo-Betancor O, Soto-Ortolaza AI, Walton RL, Rayaprolu S, Fujioka S, Murray ME, Heckman MG, Puschmann A, McCarthy A, Lynch T, Siuda J, Opala G, Rudzinska M, Krygowska-Wajs A, Barcikowska M, Czyzewski K, Sanotsky Y, Rektorová I, McLean PJ, Rademakers R, Ertekin-Taner N, Hassan A, Ahlskog JE, Boeve BF, Petersen RC, Maraganore DM, Adler CH, Ferman TJ, Parisi JE, Graff-Radford NR, Uitti RJ, Wszolek ZK, Dickson DW, Ross OA. Labbé C, et al. Among authors: mclean pj. Neurology. 2015 Nov 10;85(19):1680-6. doi: 10.1212/WNL.0000000000001946. Epub 2015 Sep 2. Neurology. 2015. PMID: 26333800 Free PMC article.
Biomarkers in Parkinson's disease: Advances and strategies.
Delenclos M, Jones DR, McLean PJ, Uitti RJ. Delenclos M, et al. Among authors: mclean pj. Parkinsonism Relat Disord. 2016 Jan;22 Suppl 1(Suppl 1):S106-10. doi: 10.1016/j.parkreldis.2015.09.048. Epub 2015 Sep 30. Parkinsonism Relat Disord. 2016. PMID: 26439946 Free PMC article. Review.
Untangling a role for tau in synucleinopathies.
Delenclos M, Moussaud S, McLean PJ. Delenclos M, et al. Among authors: mclean pj. Biol Psychiatry. 2015 Nov 15;78(10):666-7. doi: 10.1016/j.biopsych.2015.08.020. Biol Psychiatry. 2015. PMID: 26497280 Free PMC article. No abstract available.
Transmission of Soluble and Insoluble α-Synuclein to Mice.
Jones DR, Delenclos M, Baine AT, DeTure M, Murray ME, Dickson DW, McLean PJ. Jones DR, et al. Among authors: mclean pj. J Neuropathol Exp Neurol. 2015 Dec;74(12):1158-69. doi: 10.1097/NEN.0000000000000262. J Neuropathol Exp Neurol. 2015. PMID: 26574670 Free PMC article.
114 results