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Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
Petersen NH, Olsen OD, Groth-Pedersen L, Ellegaard AM, Bilgin M, Redmer S, Ostenfeld MS, Ulanet D, Dovmark TH, Lønborg A, Vindeløv SD, Hanahan D, Arenz C, Ejsing CS, Kirkegaard T, Rohde M, Nylandsted J, Jäättelä M. Petersen NH, et al. Among authors: jaattela m. Cancer Cell. 2013 Sep 9;24(3):379-93. doi: 10.1016/j.ccr.2013.08.003. Cancer Cell. 2013. PMID: 24029234 Free article.
The Mutational Landscape of the Oncogenic MZF1 SCAN Domain in Cancer.
Nygaard M, Terkelsen T, Vidas Olsen A, Sora V, Salamanca Viloria J, Rizza F, Bergstrand-Poulsen S, Di Marco M, Vistesen M, Tiberti M, Lambrughi M, Jäättelä M, Kallunki T, Papaleo E. Nygaard M, et al. Among authors: jaattela m. Front Mol Biosci. 2016 Dec 15;3:78. doi: 10.3389/fmolb.2016.00078. eCollection 2016. Front Mol Biosci. 2016. PMID: 28018905 Free PMC article.
Release of transcriptional repression via ErbB2-induced, SUMO-directed phosphorylation of myeloid zinc finger-1 serine 27 activates lysosome redistribution and invasion.
Brix DM, Tvingsholm SA, Hansen MB, Clemmensen KB, Ohman T, Siino V, Lambrughi M, Hansen K, Puustinen P, Gromova I, James P, Papaleo E, Varjosalo M, Moreira J, Jäättelä M, Kallunki T. Brix DM, et al. Among authors: jaattela m. Oncogene. 2019 Apr;38(17):3170-3184. doi: 10.1038/s41388-018-0653-x. Epub 2019 Jan 8. Oncogene. 2019. PMID: 30622337 Free PMC article.
Annexin A7 is required for ESCRT III-mediated plasma membrane repair.
Sønder SL, Boye TL, Tölle R, Dengjel J, Maeda K, Jäättelä M, Simonsen AC, Jaiswal JK, Nylandsted J. Sønder SL, et al. Among authors: jaattela m. Sci Rep. 2019 Apr 30;9(1):6726. doi: 10.1038/s41598-019-43143-4. Sci Rep. 2019. PMID: 31040365 Free PMC article.
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E, Lanzetti L, De Zio D, Cecconi F. Holdgaard SG, et al. Among authors: jaattela m. Nat Commun. 2019 Sep 13;10(1):4176. doi: 10.1038/s41467-019-12094-9. Nat Commun. 2019. PMID: 31519908 Free PMC article.
SnapShot: Lysosomal Functions.
Holland LKK, Nielsen IØ, Maeda K, Jäättelä M. Holland LKK, et al. Among authors: jaattela m. Cell. 2020 Apr 30;181(3):748-748.e1. doi: 10.1016/j.cell.2020.03.043. Cell. 2020. PMID: 32359442 Free article.
206 results