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Rapid identification of highly potent human anti-GPCR antagonist monoclonal antibodies.
Scott MJ, Jowett A, Orecchia M, Ertl P, Ouro-Gnao L, Ticehurst J, Gower D, Yates J, Poulton K, Harris C, Mullin MJ, Smith KJ, Lewis AP, Barton N, Washburn ML, de Wildt R. Scott MJ, et al. Among authors: ertl p. MAbs. 2020 Jan-Dec;12(1):1755069. doi: 10.1080/19420862.2020.1755069. MAbs. 2020. PMID: 32343620 Free PMC article.
Structure-Based and Property-Driven Optimization of N-Aryl Imidazoles toward Potent and Selective Oral RORγt Inhibitors.
Hoegenauer K, Kallen J, Jiménez-Núñez E, Strang R, Ertl P, Cooke NG, Hintermann S, Voegtle M, Betschart C, McKay DJJ, Wagner J, Ottl J, Beerli C, Billich A, Dawson J, Kaupmann K, Streiff M, Gobeau N, Harlfinger S, Stringer R, Guntermann C. Hoegenauer K, et al. Among authors: ertl p. J Med Chem. 2019 Dec 12;62(23):10816-10832. doi: 10.1021/acs.jmedchem.9b01291. Epub 2019 Dec 3. J Med Chem. 2019. PMID: 31729873
Complex molecules: do they add value?
Selzer P, Roth HJ, Ertl P, Schuffenhauer A. Selzer P, et al. Among authors: ertl p. Curr Opin Chem Biol. 2005 Jun;9(3):310-6. doi: 10.1016/j.cbpa.2005.04.001. Curr Opin Chem Biol. 2005. PMID: 15939334 Review.
213 results