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EZH2-Deficient T-cell Acute Lymphoblastic Leukemia Is Sensitized to CHK1 Inhibition through Enhanced Replication Stress.
León TE, Rapoz-D'Silva T, Bertoli C, Rahman S, Magnussen M, Philip B, Farah N, Richardson SE, Ahrabi S, Guerra-Assunção JA, Gupta R, Nacheva EP, Henderson S, Herrero J, Linch DC, de Bruin RAM, Mansour MR. León TE, et al. Among authors: herrero j. Cancer Discov. 2020 Jul;10(7):998-1017. doi: 10.1158/2159-8290.CD-19-0789. Epub 2020 Apr 29. Cancer Discov. 2020. PMID: 32349972 Free PMC article.
H3.3K27M Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas.
Pathania M, De Jay N, Maestro N, Harutyunyan AS, Nitarska J, Pahlavan P, Henderson S, Mikael LG, Richard-Londt A, Zhang Y, Costa JR, Hébert S, Khazaei S, Ibrahim NS, Herrero J, Riccio A, Albrecht S, Ketteler R, Brandner S, Kleinman CL, Jabado N, Salomoni P. Pathania M, et al. Among authors: herrero j. Cancer Cell. 2017 Nov 13;32(5):684-700.e9. doi: 10.1016/j.ccell.2017.09.014. Epub 2017 Oct 26. Cancer Cell. 2017. PMID: 29107533 Free PMC article.
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Böiers C, Richardson SE, Laycock E, Zriwil A, Turati VA, Brown J, Wray JP, Wang D, James C, Herrero J, Sitnicka E, Karlsson S, Smith AJH, Jacobsen SEW, Enver T. Böiers C, et al. Among authors: herrero j. Dev Cell. 2018 Feb 5;44(3):362-377.e7. doi: 10.1016/j.devcel.2017.12.005. Epub 2017 Dec 28. Dev Cell. 2018. PMID: 29290585 Free PMC article.
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi K, de Massy MR, Ismail M, Reading JL, Uddin I, Woolston A, Hatipoglu E, Oakes T, Rosenthal R, Peacock T, Ronel T, Noursadeghi M, Turati V, Furness AJS, Georgiou A, Wong YNS, Ben Aissa A, Sunderland MW, Jamal-Hanjani M, Veeriah S, Birkbak NJ, Wilson GA, Hiley CT, Ghorani E, Guerra-Assunção JA, Herrero J, Enver T, Hadrup SR, Hackshaw A, Peggs KS, McGranahan N, Swanton C; TRACERx consortium; Quezada SA, Chain B. Joshi K, et al. Among authors: herrero j. Nat Med. 2019 Oct;25(10):1549-1559. doi: 10.1038/s41591-019-0592-2. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591606 Free PMC article.
The Personal Genome Project-UK, an open access resource of human multi-omics data.
Chervova O, Conde L, Guerra-Assunção JA, Moghul I, Webster AP, Berner A, Larose Cadieux E, Tian Y, Voloshin V, Jesus TF, Hamoudi R, Herrero J, Beck S. Chervova O, et al. Among authors: herrero j. Sci Data. 2019 Oct 31;6(1):257. doi: 10.1038/s41597-019-0205-4. Sci Data. 2019. PMID: 31672996 Free PMC article.
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Ghorani E, Reading JL, Henry JY, Massy MR, Rosenthal R, Turati V, Joshi K, Furness AJS, Ben Aissa A, Saini SK, Ramskov S, Georgiou A, Sunderland MW, Wong YNS, Mucha MV, Day W, Galvez-Cancino F, Becker PD, Uddin I, Oakes T, Ismail M, Ronel T, Woolston A, Jamal-Hanjani M, Veeriah S, Birkbak NJ, Wilson GA, Litchfield K, Conde L, Guerra-Assunção JA, Blighe K, Biswas D, Salgado R, Lund T, Bakir MA, Moore DA, Hiley CT, Loi S, Sun Y, Yuan Y, AbdulJabbar K, Turajilic S, Herrero J, Enver T, Hadrup SR, Hackshaw A, Peggs KS, McGranahan N, Chain B; TRACERx Consortium; Swanton C, Quezada SA. Ghorani E, et al. Among authors: herrero j. Nat Cancer. 2020 May;1(5):546-561. doi: 10.1038/s43018-020-0066-y. Epub 2020 May 22. Nat Cancer. 2020. PMID: 32803172 Free PMC article.
GenomeChronicler: The Personal Genome Project UK Genomic Report Generator Pipeline.
Guerra-Assunção JA, Conde L, Moghul I, Webster AP, Ecker S, Chervova O, Chatzipantsiou C, Prieto PP, Beck S, Herrero J. Guerra-Assunção JA, et al. Among authors: herrero j. Front Genet. 2020 Sep 24;11:518644. doi: 10.3389/fgene.2020.518644. eCollection 2020. Front Genet. 2020. PMID: 33193602 Free PMC article.
Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition.
Litchfield K, Reading JL, Puttick C, Thakkar K, Abbosh C, Bentham R, Watkins TBK, Rosenthal R, Biswas D, Rowan A, Lim E, Al Bakir M, Turati V, Guerra-Assunção JA, Conde L, Furness AJS, Saini SK, Hadrup SR, Herrero J, Lee SH, Van Loo P, Enver T, Larkin J, Hellmann MD, Turajlic S, Quezada SA, McGranahan N, Swanton C. Litchfield K, et al. Among authors: herrero j. Cell. 2021 Feb 4;184(3):596-614.e14. doi: 10.1016/j.cell.2021.01.002. Epub 2021 Jan 27. Cell. 2021. PMID: 33508232 Free PMC article.
The Th1 cell regulatory circuitry is largely conserved between human and mouse.
Henderson S, Pullabhatla V, Hertweck A, de Rinaldis E, Herrero J, Lord GM, Jenner RG. Henderson S, et al. Among authors: herrero j. Life Sci Alliance. 2021 Sep 16;4(11):e202101075. doi: 10.26508/lsa.202101075. Print 2021 Nov. Life Sci Alliance. 2021. PMID: 34531288 Free PMC article.
823 results