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Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study.
Ober C, McKennan CG, Magnaye KM, Altman MC, Washington C 3rd, Stanhope C, Naughton KA, Rosasco MG, Bacharier LB, Billheimer D, Gold DR, Gress L, Hartert T, Havstad S, Khurana Hershey GK, Hallmark B, Hogarth DK, Jackson DJ, Johnson CC, Kattan M, Lemanske RF, Lynch SV, Mendonca EA, Miller RL, Naureckas ET, O'Connor GT, Seroogy CM, Wegienka G, White SR, Wood RA, Wright AL, Zoratti EM, Martinez FD, Ownby D, Nicolae DL, Levin AM, Gern JE; Environmental Influences on Child Health Outcomes-Children's Respiratory Research Workgroup. Ober C, et al. Among authors: mckennan cg. Lancet Respir Med. 2020 May;8(5):482-492. doi: 10.1016/S2213-2600(20)30011-4. Lancet Respir Med. 2020. PMID: 32380068 Free PMC article.
Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age.
Morin A, McKennan CG, Pedersen CT, Stokholm J, Chawes BL, Malby Schoos AM, Naughton KA, Thorsen J, Mortensen MS, Vercelli D, Trivedi U, Sørensen SJ, Bisgaard H, Nicolae DL, Bønnelykke K, Ober C. Morin A, et al. Among authors: mckennan cg. J Allergy Clin Immunol. 2020 Dec;146(6):1358-1366. doi: 10.1016/j.jaci.2020.07.005. Epub 2020 Jul 18. J Allergy Clin Immunol. 2020. PMID: 32693091 Free PMC article. Clinical Trial.
Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels.
McKennan C, Naughton K, Stanhope C, Kattan M, O'Connor GT, Sandel MT, Visness CM, Wood RA, Bacharier LB, Beigelman A, Lovinsky-Desir S, Togias A, Gern JE, Nicolae D, Ober C. McKennan C, et al. Epigenetics. 2021 Jun;16(6):662-676. doi: 10.1080/15592294.2020.1817290. Epub 2020 Sep 30. Epigenetics. 2021. PMID: 32997571 Free PMC article.
Unconjugated bilirubin is associated with protection from early-life wheeze and childhood asthma.
Turi KN, McKennan C, Gebretsadik T, Snyder B, Seroogy CM, Lemanske RF Jr, Zoratti E, Havstad S, Ober C, Lynch S, McCauley K, Yu C, Jackson DJ, Gern JE, Hartert TV; ECHO-CREW investigators. Turi KN, et al. J Allergy Clin Immunol. 2021 Jul;148(1):128-138. doi: 10.1016/j.jaci.2020.12.639. Epub 2021 Jan 10. J Allergy Clin Immunol. 2021. PMID: 33434532 Free PMC article.
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.
Eliasen AU, Pedersen CET, Rasmussen MA, Wang N, Soverini M, Fritz A, Stokholm J, Chawes BL, Morin A, Bork-Jensen J, Grarup N, Pedersen O, Hansen T, Linneberg A, Mortensen PB, Hougaard DM, Bybjerg-Grauholm J, Bækvad-Hansen M, Mors O, Nordentoft M, Børglum AD, Werge T, Agerbo E, Söderhall C, Altman MC, Thysen AH, McKennan CG, Brix S, Gern JE, Ober C, Ahluwalia TS, Bisgaard H, Pedersen AG, Bønnelykke K. Eliasen AU, et al. Among authors: mckennan cg. J Allergy Clin Immunol. 2022 Sep;150(3):622-630. doi: 10.1016/j.jaci.2022.03.019. Epub 2022 Apr 2. J Allergy Clin Immunol. 2022. PMID: 35381269
Childhood Asthma Incidence, Early and Persistent Wheeze, and Neighborhood Socioeconomic Factors in the ECHO/CREW Consortium.
Zanobetti A, Ryan PH, Coull B, Brokamp C, Datta S, Blossom J, Lothrop N, Miller RL, Beamer PI, Visness CM, Andrews H, Bacharier LB, Hartert T, Johnson CC, Ownby D, Khurana Hershey GK, Joseph C, Yiqiang S, Mendonça EA, Jackson DJ, Luttmann-Gibson H, Zoratti EM, Wright AL, Martinez FD, Seroogy CM, Gern JE, Gold DR; Children’s Respiratory and Environmental Workgroup (CREW) Consortium. Zanobetti A, et al. JAMA Pediatr. 2022 Aug 1;176(8):759-767. doi: 10.1001/jamapediatrics.2022.1446. JAMA Pediatr. 2022. PMID: 35604671 Free PMC article.
African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans.
Washington C 3rd, Dapas M, Biddanda A, Magnaye KM, Aneas I, Helling BA, Szczesny B, Boorgula MP, Taub MA, Kenny E, Mathias RA, Barnes KC; CAAPA; Khurana Hershey GK, Kercsmar CM, Gereige JD, Makhija M, Gruchalla RS, Gill MA, Liu AH, Rastogi D, Busse W, Gergen PJ, Visness CM, Gold DR, Hartert T, Johnson CC, Lemanske RF Jr, Martinez FD, Miller RL, Ownby D, Seroogy CM, Wright AL, Zoratti EM, Bacharier LB, Kattan M, O'Connor GT, Wood RA, Nobrega MA, Altman MC, Jackson DJ, Gern JE, McKennan CG, Ober C. Washington C 3rd, et al. Among authors: mckennan cg. Genome Med. 2022 Sep 29;14(1):112. doi: 10.1186/s13073-022-01114-x. Genome Med. 2022. PMID: 36175932 Free PMC article.
24 results