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Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling.
Nakajima S, Igyártó BZ, Honda T, Egawa G, Otsuka A, Hara-Chikuma M, Watanabe N, Ziegler SF, Tomura M, Inaba K, Miyachi Y, Kaplan DH, Kabashima K. Nakajima S, et al. J Allergy Clin Immunol. 2012 Apr;129(4):1048-55.e6. doi: 10.1016/j.jaci.2012.01.063. Epub 2012 Mar 3. J Allergy Clin Immunol. 2012. PMID: 22385635 Free PMC article.
Autocrine/paracrine TGF-β1 inhibits Langerhans cell migration.
Bobr A, Igyarto BZ, Haley KM, Li MO, Flavell RA, Kaplan DH. Bobr A, et al. Proc Natl Acad Sci U S A. 2012 Jun 26;109(26):10492-7. doi: 10.1073/pnas.1119178109. Epub 2012 Jun 11. Proc Natl Acad Sci U S A. 2012. PMID: 22689996 Free PMC article.
Antigen presentation by Langerhans cells.
Igyártó BZ, Kaplan DH. Igyártó BZ, et al. Curr Opin Immunol. 2013 Feb;25(1):115-9. doi: 10.1016/j.coi.2012.11.007. Epub 2012 Dec 12. Curr Opin Immunol. 2013. PMID: 23246038 Free PMC article. Review.
Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.
Mohammed J, Beura LK, Bobr A, Astry B, Chicoine B, Kashem SW, Welty NE, Igyártó BZ, Wijeyesinghe S, Thompson EA, Matte C, Bartholin L, Kaplan A, Sheppard D, Bridges AG, Shlomchik WD, Masopust D, Kaplan DH. Mohammed J, et al. Among authors: kaplan a, kaplan dh. Nat Immunol. 2016 Apr;17(4):414-21. doi: 10.1038/ni.3396. Epub 2016 Feb 22. Nat Immunol. 2016. PMID: 26901152 Free PMC article.
3,233 results