Brochot C - Search Results

1

A generic PBTK model implemented in the MCRA platform: Predictive performance and uses in risk assessment of chemicals.

Tebby C, van der Voet H, de Sousa G, Rorije E, Kumar V, de Boer W, Kruisselbrink JW, Bois FY, Faniband M, Moretto A, Brochot C. Tebby C, et al. Among authors: brochot c. Food Chem Toxicol. 2020 Aug;142:111440. doi: 10.1016/j.fct.2020.111440. Epub 2020 May 27. Food Chem Toxicol. 2020. PMID: 32473292 Free article.

2

Extension of the isobolographic approach to interactions studies between more than two drugs: illustration with the convulsant interaction between pefloxacin, norfloxacin, and theophylline in rats.

Brochot C, Marchand S, Couet W, Gelman A, Bois FY. Brochot C, et al. J Pharm Sci. 2004 Mar;93(3):553-62. doi: 10.1002/jps.10574. J Pharm Sci. 2004. PMID: 14762894 Free article.

3

Lumping in pharmacokinetics.

Brochot C, Tóth J, Bois FY. Brochot C, et al. J Pharmacokinet Pharmacodyn. 2005 Dec;32(5-6):719-36. doi: 10.1007/s10928-005-0054-y. J Pharmacokinet Pharmacodyn. 2005. PMID: 16341473

4

Use of a chemical probe to increase safety for human volunteers in toxicokinetic studies.

Brochot C, Bois FY. Brochot C, et al. Risk Anal. 2005 Dec;25(6):1559-71. doi: 10.1111/j.1539-6924.2005.00682.x. Risk Anal. 2005. PMID: 16506982

5

Evaluation of antiangiogenic treatment effects on tumors' microcirculation by Bayesian physiological pharmacokinetic modeling and magnetic resonance imaging.

Brochot C, Bessoud B, Balvay D, Cuénod CA, Siauve N, Bois FY. Brochot C, et al. Magn Reson Imaging. 2006 Oct;24(8):1059-67. doi: 10.1016/j.mri.2006.04.002. Epub 2006 May 23. Magn Reson Imaging. 2006. PMID: 16997076

6

Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues.

Brochot C, Smith TJ, Bois FY. Brochot C, et al. Chem Biol Interact. 2007 May 1;167(3):168-83. doi: 10.1016/j.cbi.2007.02.010. Epub 2007 Feb 21. Chem Biol Interact. 2007. PMID: 17397815

7

Development of a physiologically based kinetic model for 99m-technetium-labelled carbon nanoparticles inhaled by humans.

Péry AR, Brochot C, Hoet PH, Nemmar A, Bois FY. Péry AR, et al. Among authors: brochot c. Inhal Toxicol. 2009 Nov;21(13):1099-107. doi: 10.3109/08958370902748542. Inhal Toxicol. 2009. PMID: 19814607 Free article.

8

Quantifying heterogeneity in exposure-risk relationships using exhaled breath biomarkers for 1,3-butadiene exposures.

Smith TJ, Bois FY, Lin YS, Brochot C, Micallef S, Kim D, Kelsey KT. Smith TJ, et al. Among authors: brochot c. J Breath Res. 2008 Sep;2(3):037018. doi: 10.1088/1752-7155/2/3/037018. Epub 2008 Sep 8. J Breath Res. 2008. PMID: 21386179 Free PMC article.

9

Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: application to acetaminophen injury.

Prot JM, Bunescu A, Elena-Herrmann B, Aninat C, Snouber LC, Griscom L, Razan F, Bois FY, Legallais C, Brochot C, Corlu A, Dumas ME, Leclerc E. Prot JM, et al. Among authors: brochot c. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):270-80. doi: 10.1016/j.taap.2011.12.017. Epub 2011 Dec 24. Toxicol Appl Pharmacol. 2012. PMID: 22230336 Free article.

10

In vitro human metabolism of permethrin isomers alone or as a mixture and the formation of the major metabolites in cryopreserved primary hepatocytes.

Willemin ME, Kadar A, de Sousa G, Leclerc E, Rahmani R, Brochot C. Willemin ME, et al. Among authors: brochot c. Toxicol In Vitro. 2015 Jun;29(4):803-12. doi: 10.1016/j.tiv.2015.03.003. Epub 2015 Mar 9. Toxicol In Vitro. 2015. PMID: 25765475

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