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Remdesivir (GS-5734) Is Efficacious in Cynomolgus Macaques Infected With Marburg Virus.
Porter DP, Weidner JM, Gomba L, Bannister R, Blair C, Jordan R, Wells J, Wetzel K, Garza N, Van Tongeren S, Donnelly G, Steffens J, Moreau A, Bearss J, Lee E, Bavari S, Cihlar T, Warren TK. Porter DP, et al. Among authors: garza n. J Infect Dis. 2020 Nov 9;222(11):1894-1901. doi: 10.1093/infdis/jiaa290. J Infect Dis. 2020. PMID: 32479636
Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys.
Warren TK, Jordan R, Lo MK, Ray AS, Mackman RL, Soloveva V, Siegel D, Perron M, Bannister R, Hui HC, Larson N, Strickley R, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Shurtleff AC, Retterer CJ, Gharaibeh D, Zamani R, Kenny T, Eaton BP, Grimes E, Welch LS, Gomba L, Wilhelmsen CL, Nichols DK, Nuss JE, Nagle ER, Kugelman JR, Palacios G, Doerffler E, Neville S, Carra E, Clarke MO, Zhang L, Lew W, Ross B, Wang Q, Chun K, Wolfe L, Babusis D, Park Y, Stray KM, Trancheva I, Feng JY, Barauskas O, Xu Y, Wong P, Braun MR, Flint M, McMullan LK, Chen SS, Fearns R, Swaminathan S, Mayers DL, Spiropoulou CF, Lee WA, Nichol ST, Cihlar T, Bavari S. Warren TK, et al. Among authors: garza nl. Nature. 2016 Mar 17;531(7594):381-5. doi: 10.1038/nature17180. Epub 2016 Mar 2. Nature. 2016. PMID: 26934220 Free PMC article.
Efficacy of favipiravir (T-705) in nonhuman primates infected with Ebola virus or Marburg virus.
Bixler SL, Bocan TM, Wells J, Wetzel KS, Van Tongeren SA, Dong L, Garza NL, Donnelly G, Cazares LH, Nuss J, Soloveva V, Koistinen KA, Welch L, Epstein C, Liang LF, Giesing D, Lenk R, Bavari S, Warren TK. Bixler SL, et al. Antiviral Res. 2018 Mar;151:97-104. doi: 10.1016/j.antiviral.2017.12.021. Epub 2017 Dec 28. Antiviral Res. 2018. PMID: 29289666 Free article.
Intensive Care Unit-Like Care of Nonhuman Primates with Ebola Virus Disease.
Blair PW, Kortepeter MG, Downey LG, Madar CS, Downs IL, Martins KA, Rossi F, Williams JA, Madar A, Schellhase CW, Bearss JJ, Zeng X, Bavari S, Soloveva V, Wells JB, Stuthman KS, Garza NL, Vantongeren SA, Donnelly GC, Steffens J, Kalapaca J, Wiseman P, Henry J, Marko S, Chappell M, Lugo-Roman L, Ramos-Rivera E, Hofer C, Blue E, Moore J, Fiallos J, Wetzel D, Pratt WD, Unangst T, Miller A, Sola JJ, Reisler RB, Cardile AP. Blair PW, et al. J Infect Dis. 2021 Aug 16;224(4):632-642. doi: 10.1093/infdis/jiaa781. J Infect Dis. 2021. PMID: 33367826 Free PMC article.
Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus.
Warren TK, Kane CD, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Steffens J, Gomba L, Weidner JM, Norris S, Zeng X, Bannister R, Cihlar T, Bavari S, Porter DP, Iversen PL. Warren TK, et al. Sci Rep. 2021 Sep 30;11(1):19458. doi: 10.1038/s41598-021-98971-0. Sci Rep. 2021. PMID: 34593911 Free PMC article.
Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430.
Warren TK, Wells J, Panchal RG, Stuthman KS, Garza NL, Van Tongeren SA, Dong L, Retterer CJ, Eaton BP, Pegoraro G, Honnold S, Bantia S, Kotian P, Chen X, Taubenheim BR, Welch LS, Minning DM, Babu YS, Sheridan WP, Bavari S. Warren TK, et al. Nature. 2014 Apr 17;508(7496):402-5. doi: 10.1038/nature13027. Epub 2014 Mar 2. Nature. 2014. PMID: 24590073 Free PMC article.
85 results