Houchen CW - Search Results

1

Doublecortin-like kinase 1 promotes hepatocyte clonogenicity and oncogenic programming via non-canonical β-catenin-dependent mechanism.

Ali N, Nguyen CB, Chandrakesan P, Wolf RF, Qu D, May R, Goretsky T, Fazili J, Barrett TA, Li M, Huycke MM, Bronze MS, Houchen CW. Ali N, et al. Among authors: houchen cw. Sci Rep. 2020 Jun 29;10(1):10578. doi: 10.1038/s41598-020-67401-y. Sci Rep. 2020. PMID: 32601309 Free PMC article.

2

Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.

Ali N, Allam H, Bader T, May R, Basalingappa KM, Berry WL, Chandrakesan P, Qu D, Weygant N, Bronze MS, Umar S, Janknecht R, Sureban SM, Huycke M, Houchen CW. Ali N, et al. Among authors: houchen cw. PLoS One. 2013 Nov 19;8(11):e80304. doi: 10.1371/journal.pone.0080304. eCollection 2013. PLoS One. 2013. PMID: 24260365 Free PMC article.

3

Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.

Weygant N, Qu D, Berry WL, May R, Chandrakesan P, Owen DB, Sureban SM, Ali N, Janknecht R, Houchen CW. Weygant N, et al. Among authors: houchen cw. Mol Cancer. 2014 May 6;13:103. doi: 10.1186/1476-4598-13-103. Mol Cancer. 2014. PMID: 24885928 Free PMC article.

4

Inflammatory and oncogenic roles of a tumor stem cell marker doublecortin-like kinase (DCLK1) in virus-induced chronic liver diseases.

Ali N, Chandrakesan P, Nguyen CB, Husain S, Gillaspy AF, Huycke M, Berry WL, May R, Qu D, Weygant N, Sureban SM, Bronze MS, Dhanasekaran DN, Houchen CW. Ali N, et al. Among authors: houchen cw. Oncotarget. 2015 Aug 21;6(24):20327-44. doi: 10.18632/oncotarget.3972. Oncotarget. 2015. PMID: 25948779 Free PMC article.

5

Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.

Qu D, Weygant N, May R, Chandrakesan P, Madhoun M, Ali N, Sureban SM, An G, Schlosser MJ, Houchen CW. Qu D, et al. Among authors: houchen cw. PLoS One. 2015 Aug 18;10(8):e0134212. doi: 10.1371/journal.pone.0134212. eCollection 2015. PLoS One. 2015. PMID: 26285154 Free PMC article.

6

Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.

Sureban SM, Madhoun MF, May R, Qu D, Ali N, Fazili J, Weygant N, Chandrakesan P, Ding K, Lightfoot SA, Houchen CW. Sureban SM, et al. Among authors: houchen cw. Oncotarget. 2015 Nov 10;6(35):37200-15. doi: 10.18632/oncotarget.5808. Oncotarget. 2015. PMID: 26468984 Free PMC article.

7

APSA Awardee Submission: Tumor/cancer stem cell marker doublecortin-like kinase 1 in liver diseases.

Nguyen CB, Houchen CW, Ali N. Nguyen CB, et al. Among authors: houchen cw. Exp Biol Med (Maywood). 2017 Feb;242(3):242-249. doi: 10.1177/1535370216672746. Epub 2016 Oct 4. Exp Biol Med (Maywood). 2017. PMID: 27694285 Free PMC article. Review.

8

Intestinal tuft cells regulate the ATM mediated DNA Damage response via Dclk1 dependent mechanism for crypt restitution following radiation injury.

Chandrakesan P, May R, Weygant N, Qu D, Berry WL, Sureban SM, Ali N, Rao C, Huycke M, Bronze MS, Houchen CW. Chandrakesan P, et al. Among authors: houchen cw. Sci Rep. 2016 Nov 23;6:37667. doi: 10.1038/srep37667. Sci Rep. 2016. PMID: 27876863 Free PMC article.

9

DCLK1-Isoform2 Alternative Splice Variant Promotes Pancreatic Tumor Immunosuppressive M2-Macrophage Polarization.

Chandrakesan P, Panneerselvam J, May R, Weygant N, Qu D, Berry WR, Pitts K, Stanger BZ, Rao CV, Bronze MS, Houchen CW. Chandrakesan P, et al. Among authors: houchen cw. Mol Cancer Ther. 2020 Jul;19(7):1539-1549. doi: 10.1158/1535-7163.MCT-19-0776. Epub 2020 May 5. Mol Cancer Ther. 2020. PMID: 32371580 Free PMC article.

10

(Z)-3,5,4'-Trimethoxystilbene Limits Hepatitis C and Cancer Pathophysiology by Blocking Microtubule Dynamics and Cell-Cycle Progression.

Nguyen CB, Kotturi H, Waris G, Mohammed A, Chandrakesan P, May R, Sureban S, Weygant N, Qu D, Rao CV, Dhanasekaran DN, Bronze MS, Houchen CW, Ali N. Nguyen CB, et al. Among authors: houchen cw. Cancer Res. 2016 Aug 15;76(16):4887-96. doi: 10.1158/0008-5472.CAN-15-2722. Epub 2016 Jun 10. Cancer Res. 2016. PMID: 27287718 Free PMC article.

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