Paula-Lima A - Search Results

1

Astaxanthin Counteracts Excitotoxicity and Reduces the Ensuing Increases in Calcium Levels and Mitochondrial Reactive Oxygen Species Generation.

García F, Lobos P, Ponce A, Cataldo K, Meza D, Farías P, Estay C, Oyarzun-Ampuero F, Herrera-Molina R, Paula-Lima A, Ardiles ÁO, Hidalgo C, Adasme T, Muñoz P. García F, et al. Mar Drugs. 2020 Jun 26;18(6):335. doi: 10.3390/md18060335. Mar Drugs. 2020. PMID: 32604880 Free PMC article.

2

Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF.

Paula-Lima AC, Adasme T, SanMartín C, Sebollela A, Hetz C, Carrasco MA, Ferreira ST, Hidalgo C. Paula-Lima AC, et al. Antioxid Redox Signal. 2011 Apr 1;14(7):1209-23. doi: 10.1089/ars.2010.3287. Epub 2011 Jan 6. Antioxid Redox Signal. 2011. PMID: 20712397

3

Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation.

Adasme T, Haeger P, Paula-Lima AC, Espinoza I, Casas-Alarcón MM, Carrasco MA, Hidalgo C. Adasme T, et al. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):3029-34. doi: 10.1073/pnas.1013580108. Epub 2011 Jan 31. Proc Natl Acad Sci U S A. 2011. PMID: 21282625 Free PMC article.

4

The antioxidant N-acetylcysteine prevents the mitochondrial fragmentation induced by soluble amyloid-β peptide oligomers.

Sanmartin CD, Adasme T, Hidalgo C, Paula-Lima AC. Sanmartin CD, et al. Neurodegener Dis. 2012;10(1-4):34-7. doi: 10.1159/000334901. Epub 2012 Jan 24. Neurodegener Dis. 2012. PMID: 22286146

5

Sub-lethal levels of amyloid β-peptide oligomers decrease non-transferrin-bound iron uptake and do not potentiate iron toxicity in primary hippocampal neurons.

SanMartín CD, Paula-Lima AC, Hidalgo C, Núñez MT. SanMartín CD, et al. Biometals. 2012 Aug;25(4):805-13. doi: 10.1007/s10534-012-9545-7. Epub 2012 Apr 18. Biometals. 2012. PMID: 22526560

6

Amyloid β-peptide oligomers, ryanodine receptor-mediated Ca(2+) release, and Wnt-5a/Ca(2+) signaling: opposing roles in neuronal mitochondrial dynamics?

Paula-Lima AC, Hidalgo C. Paula-Lima AC, et al. Front Cell Neurosci. 2013 Jul 30;7:120. doi: 10.3389/fncel.2013.00120. eCollection 2013. Front Cell Neurosci. 2013. PMID: 23908603 Free PMC article. No abstract available.

7

Contribution of Ca2+ release channels to hippocampal synaptic plasticity and spatial memory: potential redox modulation.

Paula-Lima AC, Adasme T, Hidalgo C. Paula-Lima AC, et al. Antioxid Redox Signal. 2014 Aug 20;21(6):892-914. doi: 10.1089/ars.2013.5796. Epub 2014 Mar 11. Antioxid Redox Signal. 2014. PMID: 24410659 Review.

8

Ryanodine receptor-mediated Ca(2+) release underlies iron-induced mitochondrial fission and stimulates mitochondrial Ca(2+) uptake in primary hippocampal neurons.

Sanmartín CD, Paula-Lima AC, García A, Barattini P, Hartel S, Núñez MT, Hidalgo C. Sanmartín CD, et al. Front Mol Neurosci. 2014 Mar 11;7:13. doi: 10.3389/fnmol.2014.00013. eCollection 2014. Front Mol Neurosci. 2014. PMID: 24653672 Free PMC article.

9

Inhibitory ryanodine prevents ryanodine receptor-mediated Ca²⁺ release without affecting endoplasmic reticulum Ca²⁺ content in primary hippocampal neurons.

Adasme T, Paula-Lima A, Hidalgo C. Adasme T, et al. Biochem Biophys Res Commun. 2015 Feb 27;458(1):57-62. doi: 10.1016/j.bbrc.2015.01.065. Epub 2015 Jan 23. Biochem Biophys Res Commun. 2015. PMID: 25623539

10

Astaxanthin Protects Primary Hippocampal Neurons against Noxious Effects of Aβ-Oligomers.

Lobos P, Bruna B, Cordova A, Barattini P, Galáz JL, Adasme T, Hidalgo C, Muñoz P, Paula-Lima A. Lobos P, et al. Neural Plast. 2016;2016:3456783. doi: 10.1155/2016/3456783. Epub 2016 Mar 1. Neural Plast. 2016. PMID: 27034843 Free PMC article.

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