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PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
Yoon H, Spinelli JB, Zaganjor E, Wong SJ, German NJ, Randall EC, Dean A, Clermont A, Paulo JA, Garcia D, Li H, Rombold O, Agar NYR, Goodyear LJ, Shaw RJ, Gygi SP, Auwerx J, Haigis MC. Yoon H, et al. Among authors: zaganjor e. Cell Metab. 2020 Aug 4;32(2):215-228.e7. doi: 10.1016/j.cmet.2020.06.017. Epub 2020 Jul 13. Cell Metab. 2020. PMID: 32663458 Free PMC article.
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.
German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG Jr, Haigis MC. German NJ, et al. Among authors: zaganjor e. Mol Cell. 2016 Sep 15;63(6):1006-20. doi: 10.1016/j.molcel.2016.08.014. Mol Cell. 2016. PMID: 27635760 Free PMC article.
Mitochondria and Cancer.
Vyas S, Zaganjor E, Haigis MC. Vyas S, et al. Among authors: zaganjor e. Cell. 2016 Jul 28;166(3):555-566. doi: 10.1016/j.cell.2016.07.002. Cell. 2016. PMID: 27471965 Free PMC article. Review.
SIRT4 Is a Regulator of Insulin Secretion.
Zaganjor E, Vyas S, Haigis MC. Zaganjor E, et al. Cell Chem Biol. 2017 Jun 22;24(6):656-658. doi: 10.1016/j.chembiol.2017.06.002. Cell Chem Biol. 2017. PMID: 28644956 Free article.
Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD.
Escudero S, Zaganjor E, Lee S, Mill CP, Morgan AM, Crawford EB, Chen J, Wales TE, Mourtada R, Luccarelli J, Bird GH, Steidl U, Engen JR, Haigis MC, Opferman JT, Walensky LD. Escudero S, et al. Among authors: zaganjor e. Mol Cell. 2018 Mar 1;69(5):729-743.e7. doi: 10.1016/j.molcel.2018.02.005. Mol Cell. 2018. PMID: 29499131 Free PMC article.
Small-Molecule Screen Identifies De Novo Nucleotide Synthesis as a Vulnerability of Cells Lacking SIRT3.
Gonzalez Herrera KN, Zaganjor E, Ishikawa Y, Spinelli JB, Yoon H, Lin JR, Satterstrom FK, Ringel A, Mulei S, Souza A, Gorham JM, Benson CC, Seidman JG, Sorger PK, Clish CB, Haigis MC. Gonzalez Herrera KN, et al. Among authors: zaganjor e. Cell Rep. 2018 Feb 20;22(8):1945-1955. doi: 10.1016/j.celrep.2018.01.076. Cell Rep. 2018. PMID: 29466723 Free PMC article.
Mitochondrial efficiency directs cell fate.
Spinelli JB, Zaganjor E. Spinelli JB, et al. Among authors: zaganjor e. Nat Cell Biol. 2022 Feb;24(2):125-126. doi: 10.1038/s41556-021-00834-3. Nat Cell Biol. 2022. PMID: 35165414 No abstract available.
33 results