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A PIP2 substitute mediates voltage sensor-pore coupling in KCNQ activation.
Liu Y, Xu X, Gao J, Naffaa MM, Liang H, Shi J, Wang HZ, Yang ND, Hou P, Zhao W, White KM, Kong W, Dou A, Cui A, Zhang G, Cohen IS, Zou X, Cui J. Liu Y, et al. Among authors: wang hz. Commun Biol. 2020 Jul 16;3(1):385. doi: 10.1038/s42003-020-1104-0. Commun Biol. 2020. PMID: 32678288 Free PMC article.
Coupling an HCN2-expressing cell to a myocyte creates a two-cell pacing unit.
Valiunas V, Kanaporis G, Valiuniene L, Gordon C, Wang HZ, Li L, Robinson RB, Rosen MR, Cohen IS, Brink PR. Valiunas V, et al. Among authors: wang hz. J Physiol. 2009 Nov 1;587(Pt 21):5211-26. doi: 10.1113/jphysiol.2009.180505. Epub 2009 Sep 7. J Physiol. 2009. PMID: 19736302 Free PMC article.
Regulation of HCN2 Current by PI3K/Akt Signaling.
Lu Z, Wang HZ, Gordon CR, Ballou LM, Lin RZ, Cohen IS. Lu Z, et al. Among authors: wang hz. Front Physiol. 2020 Nov 9;11:587040. doi: 10.3389/fphys.2020.587040. eCollection 2020. Front Physiol. 2020. PMID: 33240105 Free PMC article.
Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.
Lin Y, Grinter SZ, Lu Z, Xu X, Wang HZ, Liang H, Hou P, Gao J, Clausen C, Shi J, Zhao W, Ma Z, Liu Y, White KM, Zhao L, Kang PW, Zhang G, Cohen IS, Zou X, Cui J. Lin Y, et al. Among authors: wang hz. Proc Natl Acad Sci U S A. 2021 May 18;118(20):e2024215118. doi: 10.1073/pnas.2024215118. Proc Natl Acad Sci U S A. 2021. PMID: 33990467 Free PMC article.
768 results