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Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. Northey JJ, et al. Among authors: littlepage le. J Clin Invest. 2020 Nov 2;130(11):5721-5737. doi: 10.1172/JCI129249. J Clin Invest. 2020. PMID: 32721948 Free PMC article. Clinical Trial.
Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer.
Dai C, Charlestin V, Wang M, Walker ZT, Miranda-Vergara MC, Facchine BA, Wu J, Kaliney WJ, Dovichi NJ, Li J, Littlepage LE. Dai C, et al. Among authors: littlepage le. Cancer Res. 2020 Oct 1;80(19):4071-4086. doi: 10.1158/0008-5472.CAN-19-2269. Epub 2020 Jul 6. Cancer Res. 2020. PMID: 32631905 Free PMC article.
The transcription factor ZNF217 is a prognostic biomarker and therapeutic target during breast cancer progression.
Littlepage LE, Adler AS, Kouros-Mehr H, Huang G, Chou J, Krig SR, Griffith OL, Korkola JE, Qu K, Lawson DA, Xue Q, Sternlicht MD, Dijkgraaf GJ, Yaswen P, Rugo HS, Sweeney CA, Collins CC, Gray JW, Chang HY, Werb Z. Littlepage LE, et al. Cancer Discov. 2012 Jul;2(7):638-51. doi: 10.1158/2159-8290.CD-12-0093. Epub 2012 May 10. Cancer Discov. 2012. PMID: 22728437 Free PMC article.
The effect of marrow secretome and culture environment on the rate of metastatic breast cancer cell migration in two and three dimensions.
Curtis KJ, Mai C, Martin H, Oberman AG, Alderfer L, Romero-Moreno R, Walsh M, Mitros SF, Thomas SG, Dynako JA, Zimmer DI, McNamara LM, Littlepage LE, Niebur GL. Curtis KJ, et al. Among authors: littlepage le. Mol Biol Cell. 2021 May 1;32(10):1009-1019. doi: 10.1091/mbc.E19-12-0682. Epub 2021 Mar 10. Mol Biol Cell. 2021. PMID: 33689396 Free PMC article.
37 results