Yang H - Search Results

1

Quantitation of 2-hydroxyglutarate in human plasma via LC-MS/MS using a surrogate analyte approach.

Yin F, Ling Y, Keller J, Kraus D, Narayanaswamy R, Mangus H, Li F, Yang H, Liu G. Yin F, et al. Among authors: yang h. Bioanalysis. 2020 Aug;12(16):1149-1159. doi: 10.4155/bio-2020-0131. Epub 2020 Aug 6. Bioanalysis. 2020. PMID: 32757862

2

A fit-for-purpose LC-MS/MS method for the simultaneous quantitation of ATP and 2,3-DPG in human K₂EDTA whole blood.

Kim H, Kosinski P, Kung C, Dang L, Chen Y, Yang H, Chen YS, Kramer J, Liu G. Kim H, et al. Among authors: yang h. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:89-96. doi: 10.1016/j.jchromb.2017.07.010. Epub 2017 Jul 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 28711785

3

Pharmacokinetic/Pharmacodynamic Evaluation of Ivosidenib or Enasidenib Combined With Intensive Induction and Consolidation Chemotherapy in Patients With Newly Diagnosed IDH1/2-Mutant Acute Myeloid Leukemia.

Fan B, Chen Y, Yin F, Hua L, Almon C, Nabhan S, Cooper M, Yang H, Hossain M. Fan B, et al. Among authors: yang h. Clin Pharmacol Drug Dev. 2022 Apr;11(4):429-441. doi: 10.1002/cpdd.1067. Epub 2022 Feb 14. Clin Pharmacol Drug Dev. 2022. PMID: 35166065 Free PMC article. Clinical Trial.

4

Clinical pharmacokinetics and pharmacodynamics of ivosidenib, an oral, targeted inhibitor of mutant IDH1, in patients with advanced solid tumors.

Fan B, Mellinghoff IK, Wen PY, Lowery MA, Goyal L, Tap WD, Pandya SS, Manyak E, Jiang L, Liu G, Nimkar T, Gliser C, Prahl Judge M, Agresta S, Yang H, Dai D. Fan B, et al. Among authors: yang h. Invest New Drugs. 2020 Apr;38(2):433-444. doi: 10.1007/s10637-019-00771-x. Epub 2019 Apr 26. Invest New Drugs. 2020. PMID: 31028664 Free PMC article. Clinical Trial.

5

Clinical pharmacokinetics and pharmacodynamics of ivosidenib in patients with advanced hematologic malignancies with an IDH1 mutation.

Fan B, Dai D, DiNardo CD, Stein E, de Botton S, Attar EC, Liu H, Liu G, Lemieux I, Agresta SV, Yang H. Fan B, et al. Among authors: yang h. Cancer Chemother Pharmacol. 2020 May;85(5):959-968. doi: 10.1007/s00280-020-04064-6. Epub 2020 Apr 15. Cancer Chemother Pharmacol. 2020. PMID: 32296873 Clinical Trial.

6

Effect of Mild and Moderate Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of a Single Dose of Oral Ivosidenib in Otherwise Healthy Participants.

Fan B, Dai D, Cohen M, Xu H, Yin F, Nagaraja R, Mobilia M, Almon C, Basile FG, Yang H. Fan B, et al. Among authors: yang h. Clin Pharmacol Drug Dev. 2021 Jan;10(1):99-109. doi: 10.1002/cpdd.821. Epub 2020 Jul 9. Clin Pharmacol Drug Dev. 2021. PMID: 32648303 Clinical Trial.

7

Population pharmacokinetic and exposure-response analyses of ivosidenib in patients with IDH1-mutant advanced hematologic malignancies.

Jiang X, Wada R, Poland B, Kleijn HJ, Fan B, Liu G, Liu H, Kapsalis S, Yang H, Le K. Jiang X, et al. Among authors: yang h. Clin Transl Sci. 2021 May;14(3):942-953. doi: 10.1111/cts.12959. Epub 2021 Jan 25. Clin Transl Sci. 2021. PMID: 33493392 Free PMC article. Clinical Trial.

8

Effect of itraconazole, food, and ethnic origin on the pharmacokinetics of ivosidenib in healthy subjects.

Dai D, Yang H, Nabhan S, Liu H, Hickman D, Liu G, Zacher J, Vutikullird A, Prakash C, Agresta S, Bowden C, Fan B. Dai D, et al. Among authors: yang h. Eur J Clin Pharmacol. 2019 Aug;75(8):1099-1108. doi: 10.1007/s00228-019-02673-6. Epub 2019 Apr 23. Eur J Clin Pharmacol. 2019. PMID: 31011758 Clinical Trial.

9

A novel liquid chromatography/tandem mass spectrometry based depletion method for measuring red blood cell partitioning of pharmaceutical compounds in drug discovery.

Yu S, Li S, Yang H, Lee F, Wu JT, Qian MG. Yu S, et al. Among authors: yang h. Rapid Commun Mass Spectrom. 2005;19(2):250-4. doi: 10.1002/rcm.1777. Rapid Commun Mass Spectrom. 2005. PMID: 15609367

10

Pharmacokinetics, absorption, metabolism, and excretion of [¹⁴C]ivosidenib (AG-120) in healthy male subjects.

Prakash C, Fan B, Altaf S, Agresta S, Liu H, Yang H. Prakash C, et al. Among authors: yang h. Cancer Chemother Pharmacol. 2019 May;83(5):837-848. doi: 10.1007/s00280-019-03793-7. Epub 2019 Feb 13. Cancer Chemother Pharmacol. 2019. PMID: 30758648 Clinical Trial.

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