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Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells.
Shin SH, Lee JS, Zhang JM, Choi S, Boskovic ZV, Zhao R, Song M, Wang R, Tian J, Lee MH, Kim JH, Jeong M, Lee JH, Petukhov M, Lee SW, Kim SG, Zou L, Byun S. Shin SH, et al. Among authors: lee sw, lee js, lee mh, lee jh. Sci Adv. 2020 Jul 31;6(31):eaay9131. doi: 10.1126/sciadv.aay9131. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32789167 Free PMC article.
USP8 is a novel target for overcoming gefitinib resistance in lung cancer.
Byun S, Lee SY, Lee J, Jeong CH, Farrand L, Lim S, Reddy K, Kim JY, Lee MH, Lee HJ, Bode AM, Won Lee K, Dong Z. Byun S, et al. Among authors: lee sy, lee mh, lee j, lee hj. Clin Cancer Res. 2013 Jul 15;19(14):3894-904. doi: 10.1158/1078-0432.CCR-12-3696. Epub 2013 Jun 7. Clin Cancer Res. 2013. PMID: 23748694 Free PMC article.
The P110 subunit of PI3-K is a therapeutic target of acacetin in skin cancer.
Jung SK, Kim JE, Lee SY, Lee MH, Byun S, Kim YA, Lim TG, Reddy K, Huang Z, Bode AM, Lee HJ, Lee KW, Dong Z. Jung SK, et al. Among authors: lee sy, lee mh, lee kw, lee hj. Carcinogenesis. 2014 Jan;35(1):123-30. doi: 10.1093/carcin/bgt266. Epub 2013 Aug 2. Carcinogenesis. 2014. PMID: 23913940 Free PMC article.
Targeting AKT with Oridonin Inhibits Growth of Esophageal Squamous Cell Carcinoma In Vitro and Patient-Derived Xenografts In Vivo.
Song M, Liu X, Liu K, Zhao R, Huang H, Shi Y, Zhang M, Zhou S, Xie H, Chen H, Li Y, Zheng Y, Wu Q, Liu F, Li E, Bode AM, Dong Z, Lee MH. Song M, et al. Among authors: lee mh. Mol Cancer Ther. 2018 Jul;17(7):1540-1553. doi: 10.1158/1535-7163.MCT-17-0823. Epub 2018 Apr 25. Mol Cancer Ther. 2018. PMID: 29695636 Free PMC article.
Inhibiting breast cancer by targeting the thromboxane A2 pathway.
Li H, Lee MH, Liu K, Wang T, Song M, Han Y, Yao K, Xie H, Zhu F, Grossmann M, Cleary MP, Chen W, Bode AM, Dong Z. Li H, et al. Among authors: lee mh. NPJ Precis Oncol. 2017 Apr 3;1(1):8. doi: 10.1038/s41698-017-0011-4. eCollection 2017. NPJ Precis Oncol. 2017. PMID: 29872696 Free PMC article.
5,229 results