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The ubiquitin-like modifier FAT10 inhibits retinal PDE6 activity and mediates its proteasomal degradation.
J Biol Chem. 2020 Oct 16;295(42):14402-14418. doi: 10.1074/jbc.RA120.013873. Epub 2020 Aug 14.
J Biol Chem. 2020.
PMID: 32817338
Free PMC article.
The ubiquitin-like modifier FAT10 stimulates the activity of deubiquitylating enzyme OTUB1.
Bialas J, Boehm AN, Catone N, Aichem A, Groettrup M.
Bialas J, et al. Among authors: boehm an.
J Biol Chem. 2019 Mar 22;294(12):4315-4330. doi: 10.1074/jbc.RA118.005406. Epub 2019 Feb 4.
J Biol Chem. 2019.
PMID: 30718280
Free PMC article.
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Analysis of modification and proteolytic targeting by the ubiquitin-like modifier FAT10.
Aichem A, Boehm AN, Catone N, Schmidtke G, Groettrup M.
Aichem A, et al. Among authors: boehm an.
Methods Enzymol. 2019;618:229-256. doi: 10.1016/bs.mie.2018.12.040. Epub 2019 Feb 8.
Methods Enzymol. 2019.
PMID: 30850054
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The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6.
Sacristan-Reviriego A, Bellingham J, Prodromou C, Boehm AN, Aichem A, Kumaran N, Bainbridge J, Michaelides M, van der Spuy J.
Sacristan-Reviriego A, et al. Among authors: boehm an.
Hum Mol Genet. 2017 Nov 15;26(22):4465-4480. doi: 10.1093/hmg/ddx334.
Hum Mol Genet. 2017.
PMID: 28973376
Free PMC article.
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The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6.
Sacristan-Reviriego A, Bellingham J, Prodromou C, Boehm AN, Aichem A, Kumaran N, Bainbridge J, Michaelides M, van der Spuy J.
Sacristan-Reviriego A, et al. Among authors: boehm an.
Hum Mol Genet. 2018 Apr 1;27(7):1309. doi: 10.1093/hmg/ddy024.
Hum Mol Genet. 2018.
PMID: 29351602
Free PMC article.
No abstract available.
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