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Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum-mitochondria tether.
Naon D, Zaninello M, Giacomello M, Varanita T, Grespi F, Lakshminaranayan S, Serafini A, Semenzato M, Herkenne S, Hernández-Alvarez MI, Zorzano A, De Stefani D, Dorn GW 2nd, Scorrano L. Naon D, et al. Among authors: de stefani d. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11249-11254. doi: 10.1073/pnas.1606786113. Epub 2016 Sep 19. Proc Natl Acad Sci U S A. 2016. PMID: 27647893 Free PMC article.
Reply to Filadi et al.: Does Mitofusin 2 tether or separate endoplasmic reticulum and mitochondria?
Naon D, Zaninello M, Giacomello M, Varanita T, Grespi F, Lakshminaranayan S, Serafini A, Semenzato M, Herkenne S, Hernández-Alvarez MI, Zorzano A, De Stefani D, Dorn GW 2nd, Scorrano L. Naon D, et al. Among authors: de stefani d. Proc Natl Acad Sci U S A. 2017 Mar 21;114(12):E2268-E2269. doi: 10.1073/pnas.1618610114. Epub 2017 Mar 13. Proc Natl Acad Sci U S A. 2017. PMID: 28289205 Free PMC article. No abstract available.
MFN2 mutations in Charcot-Marie-Tooth disease alter mitochondria-associated ER membrane function but do not impair bioenergetics.
Larrea D, Pera M, Gonnelli A, Quintana-Cabrera R, Akman HO, Guardia-Laguarta C, Velasco KR, Area-Gomez E, Dal Bello F, De Stefani D, Horvath R, Shy ME, Schon EA, Giacomello M. Larrea D, et al. Among authors: de stefani d. Hum Mol Genet. 2019 Jun 1;28(11):1782-1800. doi: 10.1093/hmg/ddz008. Hum Mol Genet. 2019. PMID: 30649465 Free PMC article.
The mitochondrial Ca(2+) uniporter.
Raffaello A, De Stefani D, Rizzuto R. Raffaello A, et al. Among authors: de stefani d. Cell Calcium. 2012 Jul;52(1):16-21. doi: 10.1016/j.ceca.2012.04.006. Epub 2012 Jun 4. Cell Calcium. 2012. PMID: 22672876 Review.
Mitochondria as sensors and regulators of calcium signalling.
Rizzuto R, De Stefani D, Raffaello A, Mammucari C. Rizzuto R, et al. Among authors: de stefani d. Nat Rev Mol Cell Biol. 2012 Sep;13(9):566-78. doi: 10.1038/nrm3412. Epub 2012 Aug 1. Nat Rev Mol Cell Biol. 2012. PMID: 22850819 Review.
Molecular control of mitochondrial calcium uptake.
De Stefani D, Rizzuto R. De Stefani D, et al. Biochem Biophys Res Commun. 2014 Jul 11;449(4):373-6. doi: 10.1016/j.bbrc.2014.04.142. Epub 2014 Apr 30. Biochem Biophys Res Commun. 2014. PMID: 24792182
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