Krenciute G - Search Results

1

What is the Optimal Design-Build-Test Cycle for Clinically Relevant Synthetic CAR T Cell Therapies?

Chen YY, Lim W, Levings M, Blazar B, Krenciute G, Wong W, Lehner M. Chen YY, et al. Among authors: krenciute g. Cell Syst. 2020 Sep 23;11(3):212-214. doi: 10.1016/j.cels.2020.08.017. Cell Syst. 2020. PMID: 32970992 Free PMC article. No abstract available.

2

CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity.

Haydar D, Ibañez-Vega J, Crawford JC, Chou CH, Guy CS, Meehl M, Yi Z, Perry S, Laxton J, Cunningham T, Langfitt D, Vogel P, DeRenzo C, Gottschalk S, Roussel MF, Thomas PG, Krenciute G. Haydar D, et al. Among authors: krenciute g. Cancer Res Commun. 2023 Dec 1;3(12):2430-2446. doi: 10.1158/2767-9764.CRC-23-0424. Cancer Res Commun. 2023. PMID: 37971169 Free PMC article.

3

Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours.

Flugel CL, Majzner RG, Krenciute G, Dotti G, Riddell SR, Wagner DL, Abou-El-Enein M. Flugel CL, et al. Among authors: krenciute g. Nat Rev Clin Oncol. 2023 Jan;20(1):49-62. doi: 10.1038/s41571-022-00704-3. Epub 2022 Nov 23. Nat Rev Clin Oncol. 2023. PMID: 36418477 Free PMC article. Review.

4

Synapse-tuned CARs enhance immune cell anti-tumor activity.

Chockley PJ, Ibanez-Vega J, Krenciute G, Talbot LJ, Gottschalk S. Chockley PJ, et al. Among authors: krenciute g. Nat Biotechnol. 2023 Oct;41(10):1434-1445. doi: 10.1038/s41587-022-01650-2. Epub 2023 Feb 2. Nat Biotechnol. 2023. PMID: 36732477

5

CD47 expression is critical for CAR T-cell survival in vivo.

Beckett AN, Chockley P, Pruett-Miller SM, Nguyen P, Vogel P, Sheppard H, Krenciute G, Gottschalk S, DeRenzo C. Beckett AN, et al. Among authors: krenciute g. J Immunother Cancer. 2023 Mar;11(3):e005857. doi: 10.1136/jitc-2022-005857. J Immunother Cancer. 2023. PMID: 36918226 Free PMC article.

6

Hypoxia-inducible CAR expression: An answer to the on-target/off-tumor dilemma?

Prinzing B, Krenciute G. Prinzing B, et al. Among authors: krenciute g. Cell Rep Med. 2021 Apr 20;2(4):100244. doi: 10.1016/j.xcrm.2021.100244. eCollection 2021 Apr 20. Cell Rep Med. 2021. PMID: 33948575 Free PMC article.

7

GRP78-CAR T cell effector function against solid and brain tumors is controlled by GRP78 expression on T cells.

Ibanez J, Hebbar N, Thanekar U, Yi Z, Houke H, Ward M, Nevitt C, Tian L, Mack SC, Sheppard H, Chiang J, Velasquez MP, Krenciute G. Ibanez J, et al. Among authors: krenciute g. Cell Rep Med. 2023 Nov 21;4(11):101297. doi: 10.1016/j.xcrm.2023.101297. Cell Rep Med. 2023. PMID: 37992682 Free PMC article.

8

Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants.

Krenciute G, Prinzing BL, Yi Z, Wu MF, Liu H, Dotti G, Balyasnikova IV, Gottschalk S. Krenciute G, et al. Cancer Immunol Res. 2017 Jul;5(7):571-581. doi: 10.1158/2326-6066.CIR-16-0376. Epub 2017 May 26. Cancer Immunol Res. 2017. PMID: 28550091 Free PMC article.

9

Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent.

Gomes-Silva D, Mukherjee M, Srinivasan M, Krenciute G, Dakhova O, Zheng Y, Cabral JMS, Rooney CM, Orange JS, Brenner MK, Mamonkin M. Gomes-Silva D, et al. Among authors: krenciute g. Cell Rep. 2017 Oct 3;21(1):17-26. doi: 10.1016/j.celrep.2017.09.015. Cell Rep. 2017. PMID: 28978471 Free PMC article.

10

CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?

Prinzing BL, Gottschalk SM, Krenciute G. Prinzing BL, et al. Among authors: krenciute g. Expert Rev Anticancer Ther. 2018 May;18(5):451-461. doi: 10.1080/14737140.2018.1451749. Epub 2018 Mar 16. Expert Rev Anticancer Ther. 2018. PMID: 29533108 Free PMC article. Review.

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