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Identification of Actionable Fusions as an Anti-EGFR Resistance Mechanism Using a Circulating Tumor DNA Assay.
Clifton K, Rich TA, Parseghian C, Raymond VM, Dasari A, Pereira AAL, Willis J, Loree JM, Bauer TM, Chae YK, Sherrill G, Fanta P, Grothey A, Hendifar A, Henry D, Mahadevan D, Nezami MA, Tan B, Wainberg ZA, Lanman R, Kopetz S, Morris V. Clifton K, et al. Among authors: parseghian c. JCO Precis Oncol. 2019 Oct 3;3:PO.19.00141. doi: 10.1200/PO.19.00141. eCollection 2019. JCO Precis Oncol. 2019. PMID: 33015522 Free PMC article.
Dual Inhibition of EGFR and c-Src by Cetuximab and Dasatinib Combined with FOLFOX Chemotherapy in Patients with Metastatic Colorectal Cancer.
Parseghian CM, Parikh NU, Wu JY, Jiang ZQ, Henderson L, Tian F, Pastor B, Ychou M, Raghav K, Dasari A, Fogelman DR, Katsiampoura AD, Menter DG, Wolff RA, Eng C, Overman MJ, Thierry AR, Gallick GE, Kopetz S. Parseghian CM, et al. Clin Cancer Res. 2017 Aug 1;23(15):4146-4154. doi: 10.1158/1078-0432.CCR-16-3138. Epub 2017 Mar 9. Clin Cancer Res. 2017. PMID: 28280091 Free PMC article. Clinical Trial.
Circulating DNA Demonstrates Convergent Evolution and Common Resistance Mechanisms during Treatment of Colorectal Cancer.
Thierry AR, Pastor B, Jiang ZQ, Katsiampoura AD, Parseghian C, Loree JM, Overman MJ, Sanchez C, Messaoudi SE, Ychou M, Kopetz S. Thierry AR, et al. Among authors: parseghian c. Clin Cancer Res. 2017 Aug 15;23(16):4578-4591. doi: 10.1158/1078-0432.CCR-17-0232. Epub 2017 Apr 11. Clin Cancer Res. 2017. PMID: 28400427 Free PMC article. Clinical Trial.
Anti-EGFR-resistant clones decay exponentially after progression: implications for anti-EGFR re-challenge.
Parseghian CM, Loree JM, Morris VK, Liu X, Clifton KK, Napolitano S, Henry JT, Pereira AA, Vilar E, Johnson B, Kee B, Raghav K, Dasari A, Wu J, Garg N, Raymond VM, Banks KC, Talasaz AA, Lanman RB, Strickler JH, Hong DS, Corcoran RB, Overman MJ, Kopetz S. Parseghian CM, et al. Ann Oncol. 2019 Feb 1;30(2):243-249. doi: 10.1093/annonc/mdy509. Ann Oncol. 2019. PMID: 30462160 Free PMC article.
Atypical, Non-V600 BRAF Mutations as a Potential Mechanism of Resistance to EGFR Inhibition in Metastatic Colorectal Cancer.
Johnson B, Loree JM, Jacome AA, Mendis S, Syed M, Morris Ii VK, Parseghian CM, Dasari A, Pant S, Raymond VM, Vilar E, Overman M, Kee B, Eng C, Raghav K, Kopetz S. Johnson B, et al. Among authors: parseghian cm. JCO Precis Oncol. 2019 Aug 5;3:PO.19.00102. doi: 10.1200/PO.19.00102. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32914034 Free PMC article.
Pilot Clinical Trial of Perioperative Durvalumab and Tremelimumab in the Treatment of Resectable Colorectal Cancer Liver Metastases.
Kanikarla Marie P, Haymaker C, Parra ER, Kim YU, Lazcano R, Gite S, Lorenzini D, Wistuba II, Tidwell RSS, Song X, Foo WC, Maru DM, Chun YS, Futreal A, Kee B, Menter D, Solis L, Tzeng CW, Parseghian C, Raghav K, Morris V, Chang CC, Jenq R, Tam A, Bernatchez C, Kopetz S, Vauthey JN, Overman MJ. Kanikarla Marie P, et al. Among authors: parseghian c. Clin Cancer Res. 2021 Jun 1;27(11):3039-3049. doi: 10.1158/1078-0432.CCR-21-0163. Epub 2021 Apr 2. Clin Cancer Res. 2021. PMID: 33811152 Free PMC article. Clinical Trial.
Comprehensive Clinical and Molecular Characterization of KRAS G12C-Mutant Colorectal Cancer.
Henry JT, Coker O, Chowdhury S, Shen JP, Morris VK, Dasari A, Raghav K, Nusrat M, Kee B, Parseghian C, Pant S, Jeyakumar N, Zhu L, Nishioka Y, Fogelman D, Wolff RA, Hong D, Overman MJ, Vauthey J, Kopetz S, Johnson B. Henry JT, et al. Among authors: parseghian c. JCO Precis Oncol. 2021 Apr 6;5:PO.20.00256. doi: 10.1200/PO.20.00256. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34250391 Free PMC article.
31 results