Martin-Requero Á - Search Results

1

Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis.

Rojas-Prats E, Martinez-Gonzalez L, Gonzalo-Consuegra C, Liachko NF, Perez C, Ramírez D, Kraemer BC, Martin-Requero Á, Perez DI, Gil C, de Lago E, Martinez A. Rojas-Prats E, et al. Eur J Med Chem. 2021 Jan 15;210:112968. doi: 10.1016/j.ejmech.2020.112968. Epub 2020 Oct 28. Eur J Med Chem. 2021. PMID: 33139113

2

Targeting TDP-43 phosphorylation by Casein Kinase-1δ inhibitors: a novel strategy for the treatment of frontotemporal dementia.

Alquezar C, Salado IG, de la Encarnación A, Pérez DI, Moreno F, Gil C, de Munain AL, Martínez A, Martín-Requero Á. Alquezar C, et al. Mol Neurodegener. 2016 Apr 30;11(1):36. doi: 10.1186/s13024-016-0102-7. Mol Neurodegener. 2016. PMID: 27138926 Free PMC article.

3

Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease.

Del Cerro P, Alquézar C, Bartolomé F, González-Naranjo P, Pérez C, Carro E, Páez JA, Campillo NE, Martín-Requero Á. Del Cerro P, et al. CNS Drugs. 2018 Jun;32(6):579-591. doi: 10.1007/s40263-018-0515-7. CNS Drugs. 2018. PMID: 29736745

4

Recapitulation of Pathological TDP-43 Features in Immortalized Lymphocytes from Sporadic ALS Patients.

Posa D, Martínez-González L, Bartolomé F, Nagaraj S, Porras G, Martínez A, Martín-Requero Á. Posa D, et al. Mol Neurobiol. 2019 Apr;56(4):2424-2432. doi: 10.1007/s12035-018-1249-8. Epub 2018 Jul 20. Mol Neurobiol. 2019. PMID: 30030753

5

Indazolylketones as new multitarget cannabinoid drugs.

González-Naranjo P, Pérez-Macias N, Pérez C, Roca C, Vaca G, Girón R, Sánchez-Robles E, Martín-Fontelles MI, de Ceballos ML, Martin-Requero A, Campillo NE, Páez JA. González-Naranjo P, et al. Eur J Med Chem. 2019 Mar 15;166:90-107. doi: 10.1016/j.ejmech.2019.01.030. Epub 2019 Jan 17. Eur J Med Chem. 2019. PMID: 30685536

6

TDP-43: A Key Therapeutic Target beyond Amyotrophic Lateral Sclerosis.

Palomo V, Tosat-Bitrian C, Nozal V, Nagaraj S, Martin-Requero A, Martinez A. Palomo V, et al. ACS Chem Neurosci. 2019 Mar 20;10(3):1183-1196. doi: 10.1021/acschemneuro.9b00026. Epub 2019 Mar 4. ACS Chem Neurosci. 2019. PMID: 30785719 Free article. Review.

7

Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations.

Nuñez-Borque E, González-Naranjo P, Bartolomé F, Alquézar C, Reinares-Sebastián A, Pérez C, Ceballos ML, Páez JA, Campillo NE, Martín-Requero Á. Nuñez-Borque E, et al. Mol Neurobiol. 2020 Apr;57(4):1938-1951. doi: 10.1007/s12035-019-01813-4. Epub 2020 Jan 3. Mol Neurobiol. 2020. PMID: 31898159 Free article.

8

Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment.

Martínez-González L, Rodríguez-Cueto C, Cabezudo D, Bartolomé F, Andrés-Benito P, Ferrer I, Gil C, Martín-Requero Á, Fernández-Ruiz J, Martínez A, de Lago E. Martínez-González L, et al. Sci Rep. 2020 Mar 10;10(1):4449. doi: 10.1038/s41598-020-61265-y. Sci Rep. 2020. PMID: 32157143 Free PMC article.

9

Therapeutic potential of novel Cell Division Cycle Kinase 7 inhibitors on TDP-43-related pathogenesis such as Frontotemporal Lobar Degeneration (FTLD) and amyotrophic lateral sclerosis (ALS).

Vaca G, Martinez-Gonzalez L, Fernandez A, Rojas-Prats E, Porras G, Cuevas EP, Gil C, Martinez A, Martin-Requero Á. Vaca G, et al. J Neurochem. 2021 Feb;156(3):379-390. doi: 10.1111/jnc.15118. Epub 2020 Jul 17. J Neurochem. 2021. PMID: 32628315 Free article.

10

Molecular Alterations in Sporadic and SOD1-ALS Immortalized Lymphocytes: Towards a Personalized Therapy.

Lastres-Becker I, Porras G, Arribas-Blázquez M, Maestro I, Borrego-Hernández D, Boya P, Cerdán S, García-Redondo A, Martínez A, Martin-Requero Á. Lastres-Becker I, et al. Int J Mol Sci. 2021 Mar 16;22(6):3007. doi: 10.3390/ijms22063007. Int J Mol Sci. 2021. PMID: 33809456 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

77 results

Search Page