Alvarez JV - Search Results

1

G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program.

Mabe NW, Garcia NMG, Wolery SE, Newcomb R, Meingasner RC, Vilona BA, Lupo R, Lin CC, Chi JT, Alvarez JV. Mabe NW, et al. Among authors: alvarez jv. Cell Rep. 2020 Nov 3;33(5):108341. doi: 10.1016/j.celrep.2020.108341. Cell Rep. 2020. PMID: 33147463 Free PMC article.

2

Par-4 downregulation promotes breast cancer recurrence by preventing multinucleation following targeted therapy.

Alvarez JV, Pan TC, Ruth J, Feng Y, Zhou A, Pant D, Grimley JS, Wandless TJ, Demichele A; I-SPY 1 TRIAL Investigators; Chodosh LA. Alvarez JV, et al. Cancer Cell. 2013 Jul 8;24(1):30-44. doi: 10.1016/j.ccr.2013.05.007. Epub 2013 Jun 13. Cancer Cell. 2013. PMID: 23770012 Free PMC article.

3

SPSB1 promotes breast cancer recurrence by potentiating c-MET signaling.

Feng Y, Pan TC, Pant DK, Chakrabarti KR, Alvarez JV, Ruth JR, Chodosh LA. Feng Y, et al. Among authors: alvarez jv. Cancer Discov. 2014 Jul;4(7):790-803. doi: 10.1158/2159-8290.CD-13-0548. Epub 2014 Apr 30. Cancer Discov. 2014. PMID: 24786206 Free PMC article.

4

Foxo-dependent Par-4 Upregulation Prevents Long-term Survival of Residual Cells Following PI3K-Akt Inhibition.

Damrauer JS, Phelps SN, Amuchastegui K, Lupo R, Mabe NW, Walens A, Kroger BR, Alvarez JV. Damrauer JS, et al. Among authors: alvarez jv. Mol Cancer Res. 2018 Apr;16(4):599-609. doi: 10.1158/1541-7786.MCR-17-0492. Epub 2018 Jan 12. Mol Cancer Res. 2018. PMID: 29330285 Free PMC article.

5

Epigenetic silencing of tumor suppressor Par-4 promotes chemoresistance in recurrent breast cancer.

Mabe NW, Fox DB, Lupo R, Decker AE, Phelps SN, Thompson JW, Alvarez JV. Mabe NW, et al. Among authors: alvarez jv. J Clin Invest. 2018 Oct 1;128(10):4413-4428. doi: 10.1172/JCI99481. Epub 2018 Aug 27. J Clin Invest. 2018. PMID: 30148456 Free PMC article.

6

CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors.

Walens A, DiMarco AV, Lupo R, Kroger BR, Damrauer JS, Alvarez JV. Walens A, et al. Among authors: alvarez jv. Elife. 2019 Apr 16;8:e43653. doi: 10.7554/eLife.43653. Elife. 2019. PMID: 30990165 Free PMC article.

7

RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence.

Lin CC, Mabe NW, Lin YT, Yang WH, Tang X, Hong L, Sun T, Force J, Marks JR, Yao TP, Alvarez JV, Chi JT. Lin CC, et al. Among authors: alvarez jv. Cell Death Differ. 2020 Jul;27(7):2234-2247. doi: 10.1038/s41418-020-0499-y. Epub 2020 Jan 27. Cell Death Differ. 2020. PMID: 31988496 Free PMC article.

8

NRF2 activation promotes the recurrence of dormant tumour cells through regulation of redox and nucleotide metabolism.

Fox DB, Garcia NMG, McKinney BJ, Lupo R, Noteware LC, Newcomb R, Liu J, Locasale JW, Hirschey MD, Alvarez JV. Fox DB, et al. Among authors: alvarez jv. Nat Metab. 2020 Apr;2(4):318-334. doi: 10.1038/s42255-020-0191-z. Epub 2020 Apr 20. Nat Metab. 2020. PMID: 32691018 Free PMC article.

9

Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence.

Walens A, Lin J, Damrauer JS, McKinney B, Lupo R, Newcomb R, Fox DB, Mabe NW, Gresham J, Sheng Z, Sibley AB, De Buysscher T, Kelkar H, Mieczkowski PA, Owzar K, Alvarez JV. Walens A, et al. Among authors: alvarez jv. Nat Commun. 2020 Oct 6;11(1):5017. doi: 10.1038/s41467-020-18730-z. Nat Commun. 2020. PMID: 33024122 Free PMC article.

10

DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway.

Lin CC, Yang WH, Lin YT, Tang X, Chen PH, Ding CC, Qu DC, Alvarez JV, Chi JT. Lin CC, et al. Among authors: alvarez jv. Oncogene. 2021 Mar;40(11):2018-2034. doi: 10.1038/s41388-021-01676-x. Epub 2021 Feb 18. Oncogene. 2021. PMID: 33603168 Free PMC article.

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