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Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte-neuron lactate and ketone body shuttle systems.
Thevenet J, De Marchi U, Domingo JS, Christinat N, Bultot L, Lefebvre G, Sakamoto K, Descombes P, Masoodi M, Wiederkehr A. Thevenet J, et al. Among authors: wiederkehr a. FASEB J. 2016 May;30(5):1913-26. doi: 10.1096/fj.201500182. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839375
Using single-cell imaging, we observed an acute pronounced reduction of the mitochondrial electrical potential and a concomitant drop of the NAD(P)H signal in astrocytes, but not in neurons. ...-Thevenet, J., De Marchi, U., Santo Domingo, J., Christinat, N., Bultot, L., Le …
Using single-cell imaging, we observed an acute pronounced reduction of the mitochondrial electrical potential and a concomitant drop …
Mitochondrial lysine deacetylation promotes energy metabolism and calcium signaling in insulin-secreting cells.
De Marchi U, Galindo AN, Thevenet J, Hermant A, Bermont F, Lassueur S, Domingo JS, Kussmann M, Dayon L, Wiederkehr A. De Marchi U, et al. Among authors: wiederkehr a. FASEB J. 2019 Apr;33(4):4660-4674. doi: 10.1096/fj.201801424R. Epub 2018 Dec 27. FASEB J. 2019. PMID: 30589571
-De Marchi, U., Galindo, A. N., Thevenet, J., Hermant, A., Bermont, F., Lassueur, S., Domingo, J. S., Kussmann, M., Dayon, L., Wiederkehr, A. Mitochondrial lysine deacetylation promotes energy metabolism and calcium signaling in insulin-secreting cells …
-De Marchi, U., Galindo, A. N., Thevenet, J., Hermant, A., Bermont, F., Lassueur, S., Domingo, J. S., Kussmann, M., Dayon, L., …
The plant product quinic acid activates Ca2+ -dependent mitochondrial function and promotes insulin secretion from pancreatic beta cells.
Heikkilä E, Hermant A, Thevenet J, Bermont F, Kulkarni SS, Ratajczak J, Santo-Domingo J, Dioum EH, Canto C, Barron D, Wiederkehr A, De Marchi U. Heikkilä E, et al. Among authors: wiederkehr a. Br J Pharmacol. 2019 Sep;176(17):3250-3263. doi: 10.1111/bph.14757. Epub 2019 Jul 15. Br J Pharmacol. 2019. PMID: 31166006 Free PMC article.
Macroencapsulated Human iPSC-Derived Pancreatic Progenitors Protect against STZ-Induced Hyperglycemia in Mice.
Haller C, Piccand J, De Franceschi F, Ohi Y, Bhoumik A, Boss C, De Marchi U, Jacot G, Metairon S, Descombes P, Wiederkehr A, Palini A, Bouche N, Steiner P, Kelly OG, R-C Kraus M. Haller C, et al. Among authors: wiederkehr a. Stem Cell Reports. 2019 Apr 9;12(4):787-800. doi: 10.1016/j.stemcr.2019.02.002. Epub 2019 Mar 7. Stem Cell Reports. 2019. PMID: 30853374 Free PMC article.
64 results